AIMC Topic: Tablets

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STABILITY INDICATIVE HPLC DETERMINATION OF RELATED SUBSTANCES AND IDENTIFICATION OF POTENTIAL DEGRADANTS USING LC-MS IN TRIPLE COMBINATION ANTIRETROVIRAL TABLETS.

Acta poloniae pharmaceutica
A rapid stability indicating liquid chromatography method was developed and validated for the simultaneous quantitation of related substances of antiretrovirals in combined oral dosage formulation. Separation was achieved using a Waters, Xterra RP-18...

Prediction of Dissolution Data Integrated in Tablet Database Using Four-Layered Artificial Neural Networks.

Chemical & pharmaceutical bulletin
A large number of dissolution data were measured and integrated into a previously constructed tablet database composed of 14 kinds of compounds as model active pharmaceutical ingredients (APIs) with contents ranging from 10 to 80%. The database has c...

Analysis of Closely Related Antioxidant Nutraceuticals Using the Green Analytical Methodology of ANN and Smart Spectrophotometric Methods.

Journal of AOAC International
Two new, simple, and specific green analytical methods are proposed: zero-crossing first-derivative and chemometric-based spectrophotometric artificial neural network (ANN). The proposed methods were used for the simultaneous estimation of two closel...

Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain.

Acta pharmaceutica (Zagreb, Croatia)
A novel mucoadhesive buccal tablet containing flurbiprofen (FLB) and lidocaine HCl (LID) was prepared to relieve dental pain. Tablet formulations (F1-F9) were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (...

Video tracking for high-similarity drug tablets based on reflective lightness intensity and fuzzy recognition system.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Video tracking of drug tablet exerts important influences on the efficiency and reliability of its mass production; this topic also becomes a difficult and targeted focus for pharmaceutical production monitory in the past several years due to the hig...

Optimization of Melatonin Dissolution from Extended Release Matrices Using Artificial Neural Networking.

Current drug delivery
BACKGROUND: Efficacy of melatonin in treating sleep disorders has been demonstrated in numerous studies. Being with short half-life, melatonin needs to be formulated in extended-release tablets to prevent the fast drop of its plasma concentration. Ho...

Spectrophotometric Methods for Simultaneous Determination of Amlodipine Besylate and Atenolol in Their Tablet Dosage Form.

Guang pu xue yu guang pu fen xi = Guang pu
Three simple, specific, accurate and precise spectrophotometric methods are developed for simultaneous determination of amlodipine besylate (AM) and atenolol (AT) in tablets. The first method is dual wavelength spectrophotometry (DW). The second meth...

[Fluorescence enhancement of flavoxate hydrochloride in alkali solution and its application in pharmaceutical analysis].

Yao xue xue bao = Acta pharmaceutica Sinica
Fluorescence enhancement reaction of flavoxate hydrochloride (FX) in strong alkali solution was studied, the mechanism of the reaction was investigated, and a novel fluorimetric method for analysis of FX in drug sample was established. FX has no intr...