Investigative ophthalmology & visual science
Jan 2, 2025
PURPOSE: To quantify outer retina structural changes and define novel biomarkers of inherited retinal degeneration associated with biallelic mutations in RPE65 (RPE65-IRD) in patients before and after subretinal gene augmentation therapy with voretig...
Age-related macular degeneration (AMD) is a progressive degenerative retinal disease and a leading cause of blindness in older adults worldwide. According to numerous studies, the number of affected individuals reached 196 million in 2020, with proje...
UNLABELLED: One of the priority areas in healthcare is the concept of predictive, preventive and personalized medicine, which is based on an individualized approach to the patient, including before the onset of diseases such as glaucoma.
Translational vision science & technology
Dec 2, 2024
PURPOSE: Accurate diagnosis of retinal disease based on optical coherence tomography (OCT) requires scrutiny of both B-scan and en face images. The aim of this study was to investigate the effectiveness of fusing en face and B-scan images for better ...
Translational vision science & technology
Dec 2, 2024
PURPOSE: Optical coherence tomography (OCT)-derived measurements of the optic nerve head (ONH) from different devices are not interchangeable. This poses challenges to patient follow-up and collaborative studies. Here, we present a device-agnostic me...
Journal of cataract and refractive surgery
Dec 1, 2024
PURPOSE: To differentiate a normal cornea from a forme fruste keratoconus (FFKC) with the swept-source optical coherence tomography (SS-OCT) topography CASIA 2 using machine learning artificial intelligence algorithms.
Translational vision science & technology
Nov 4, 2024
PURPOSE: The purpose of this study was to introduce SLOctolyzer: an open-source analysis toolkit for en face retinal vessels in infrared reflectance scanning laser ophthalmoscopy (SLO) images.
PURPOSE: The purpose of this study was to develop a deep learning model for predicting the axial length (AL) of eyes using optical coherence tomography (OCT) images.
PURPOSE: To use neural network machine learning (ML) models to identify the most relevant ocular biomarkers for the diagnosis of primary open-angle glaucoma (POAG).
PURPOSE: The purpose of this study was to develop a deep learning algorithm for detecting and quantifying incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) and complete retinal pigment epithelium and outer retinal atrophy (cRORA...