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Triple Negative Breast Neoplasms

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Robotic printing and drug testing of 384-well tumor spheroids.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
A major impediment to anti-cancer drug development is the lack of a reliable and inexpensive tumor model to test the efficacy of candidate compounds. This need has emerged due to the insufficiency of widely-used monolayer cultures to predict drug eff...

Machine Learning Helps Identify New Drug Mechanisms in Triple-Negative Breast Cancer.

IEEE transactions on nanobioscience
This paper demonstrates the ability of mach- ine learning approaches to identify a few genes among the 23,398 genes of the human genome to experiment on in the laboratory to establish new drug mechanisms. As a case study, this paper uses MDA-MB-231 b...