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Unsupervised Machine Learning

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Unsupervised Representation Learning for Proteochemometric Modeling.

International journal of molecular sciences
In silico protein-ligand binding prediction is an ongoing area of research in computational chemistry and machine learning based drug discovery, as an accurate predictive model could greatly reduce the time and resources necessary for the detection a...

Sheep's coping style can be identified by unsupervised machine learning from unlabeled data.

Behavioural processes
The objective of this study was to define coping style of sheep by using unsupervised machine learning approaches. A total of 105 Norduz sheep (age 3-5 years) were subjected to a 5-minute arena test. Agglomerative Hierarchical Clustering (HCA) was pe...

Making sense of the French public hospital system: a network-based approach to hospital clustering using unsupervised learning methods.

BMC health services research
BACKGROUND: Hospitals in the public and private sectors tend to join larger organizations to form hospital groups. This increasingly frequent mode of functioning raises the question of how countries should organize their health system, according to t...

High-Throughput, Label-Free and Slide-Free Histological Imaging by Computational Microscopy and Unsupervised Learning.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Rapid and high-resolution histological imaging with minimal tissue preparation has long been a challenging and yet captivating medical pursuit. Here, the authors propose a promising and transformative histological imaging method, termed computational...

Identifying clinical phenotypes in extremely low birth weight infants-an unsupervised machine learning approach.

European journal of pediatrics
There is increasing evidence that patient heterogeneity significantly hinders advancement in clinical trials and individualized care. This study aimed to identify distinct phenotypes in extremely low birth weight infants. We performed an agglomerativ...

Graph Regularized Deep Sparse Representation for Unsupervised Anomaly Detection.

Computational intelligence and neuroscience
Anomaly detection (AD) aims to distinguish the data points that are inconsistent with the overall pattern of the data. Recently, unsupervised anomaly detection methods have aroused huge attention. Among these methods, feature representation (FR) play...

Characterisation of Temporal Patterns in Step Count Behaviour from Smartphone App Data: An Unsupervised Machine Learning Approach.

International journal of environmental research and public health
The increasing ubiquity of smartphone data, with greater spatial and temporal coverage than achieved by traditional study designs, have the potential to provide insight into habitual physical activity patterns. This study implements and evaluates the...

Disease variant prediction with deep generative models of evolutionary data.

Nature
Quantifying the pathogenicity of protein variants in human disease-related genes would have a marked effect on clinical decisions, yet the overwhelming majority (over 98%) of these variants still have unknown consequences. In principle, computational...

Incremental Unsupervised Domain-Adversarial Training of Neural Networks.

IEEE transactions on neural networks and learning systems
In the context of supervised statistical learning, it is typically assumed that the training set comes from the same distribution that draws the test samples. When this is not the case, the behavior of the learned model is unpredictable and becomes d...

Analysis of the Possibilities of Tire-Defect Inspection Based on Unsupervised Learning and Deep Learning.

Sensors (Basel, Switzerland)
At present, inspection systems process visual data captured by cameras, with deep learning approaches applied to detect defects. Defect detection results usually have an accuracy higher than 94%. Real-life applications, however, are not very common. ...