Photodiagnosis and photodynamic therapy
Feb 20, 2025
BACKGROUND: The most widespread primary intraocular tumor in adults is called uveal melanoma (UM), if detected early enough, it can be curable. Various methods are available to treat UM, but the most commonly used and effective approach is plaque rad...
Experimental biology and medicine (Maywood, N.J.)
Feb 19, 2025
Advancements in machine learning and deep learning have the potential to revolutionize the diagnosis of melanocytic choroidal tumors, including uveal melanoma, a potentially life-threatening eye cancer. Traditional machine learning methods rely heavi...
PURPOSE: To evaluate ChatGPT's ability to analyze comprehensive case descriptions of patients with uveal melanoma and provide recommendations for the most appropriate management.
BACKGROUND: Although there has been some progress in the treatment of primary uveal melanoma (UVM), distant metastasis remains the leading cause of death in patients. Monitoring, staging, and treatment of metastatic disease have not yet reached conse...
Uveal melanoma (UM) patients face a significant risk of distant metastasis, closely tied to a poor prognosis. Despite this, there is a dearth of research utilizing big data to predict UM distant metastasis. This study leveraged machine learning metho...
AIMS: Uveal melanoma has a high propensity to metastasize. Prognosis is associated with specific driver mutations and copy number variations, and these can only be obtained after genetic testing. In this study we evaluated the efficacy of patient out...
BACKGROUND: Reliable differentiation of uveal melanoma and choroidal nevi is crucial to guide appropriate treatment, preventing unnecessary procedures for benign lesions and ensuring timely treatment for potentially malignant cases. The purpose of th...
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
May 18, 2024
OBJECTIVE: Uveal melanoma is the most common intraocular malignancy in adults. Current screening and triaging methods for melanocytic choroidal tumours face inherent limitations, particularly in regions with limited access to specialized ocular oncol...
BACKGROUND: Increasing evidence suggests a correlation between glycosylation and the onset of cancer. However, the clinical relevance of glycosylation-related genes (GRGs) in uveal melanoma (UM) is yet to be fully understood. This study aimed to shed...
BACKGROUND: Isolated pancreatic metastasis from melanoma is extremely uncommon and accounts for approximately only 2% of visceral disseminations of melanoma. Interestingly, pancreatic localizations disproportionately derive from primary ocular melano...