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Reproducibility of computational workflows is automated using continuous analysis.

Nature biotechnology
Replication, validation and extension of experiments are crucial for scientific progress. Computational experiments are scriptable and should be easy to reproduce. However, computational analyses are designed and run in a specific computing environme...

Knowledge as a Service at the Point of Care.

AMIA ... Annual Symposium proceedings. AMIA Symposium
An electronic health record (EHR) can assist the delivery of high-quality patient care, in part by providing the capability for a broad range of clinical decision support, including contextual references (e.g., Infobuttons), alerts and reminders, ord...

Robotic cochlear implantation: surgical procedure and first clinical experience.

Acta oto-laryngologica
CONCLUSION: A system for robotic cochlear implantation (rCI) has been developed and a corresponding surgical workflow has been described. The clinical feasibility was demonstrated through the conduction of a safe and effective rCI procedure.

SNooPer: a machine learning-based method for somatic variant identification from low-pass next-generation sequencing.

BMC genomics
BACKGROUND: Next-generation sequencing (NGS) allows unbiased, in-depth interrogation of cancer genomes. Many somatic variant callers have been developed yet accurate ascertainment of somatic variants remains a considerable challenge as evidenced by t...

An open-source solution for advanced imaging flow cytometry data analysis using machine learning.

Methods (San Diego, Calif.)
Imaging flow cytometry (IFC) enables the high throughput collection of morphological and spatial information from hundreds of thousands of single cells. This high content, information rich image data can in theory resolve important biological differe...

System events: readily accessible features for surgical phase detection.

International journal of computer assisted radiology and surgery
PURPOSE: Surgical phase recognition using sensor data is challenging due to high variation in patient anatomy and surgeon-specific operating styles. Segmenting surgical procedures into constituent phases is of significant utility for resident trainin...

Speculation detection for Chinese clinical notes: Impacts of word segmentation and embedding models.

Journal of biomedical informatics
Speculations represent uncertainty toward certain facts. In clinical texts, identifying speculations is a critical step of natural language processing (NLP). While it is a nontrivial task in many languages, detecting speculations in Chinese clinical ...

Using Semantic Components to Represent Dynamics of an Interdisciplinary Healthcare Team in a Multi-Agent Decision Support System.

Journal of medical systems
In healthcare organizations, clinical workflows are executed by interdisciplinary healthcare teams (IHTs) that operate in ways that are difficult to manage. Responding to a need to support such teams, we designed and developed the MET4 multi-agent sy...

Prediction of Protein-Protein Interaction Sites with Machine-Learning-Based Data-Cleaning and Post-Filtering Procedures.

The Journal of membrane biology
Accurately predicting protein-protein interaction sites (PPIs) is currently a hot topic because it has been demonstrated to be very useful for understanding disease mechanisms and designing drugs. Machine-learning-based computational approaches have ...

Data-driven knowledge acquisition, validation, and transformation into HL7 Arden Syntax.

Artificial intelligence in medicine
OBJECTIVE: The objective of this study is to help a team of physicians and knowledge engineers acquire clinical knowledge from existing practices datasets for treatment of head and neck cancer, to validate the knowledge against published guidelines, ...