Single-atom nanozymes (SANs) with transition metals as their core are nanomaterials characterized by atomically dispersed active sites and intrinsic enzyme-mimicking activity, exhibiting ultrahigh catalytic efficiency. As an essential trace element a...
BACKGROUND: Chronic wounds, those which have not healed in a timely manner, are a significant health and economic burden. Older people, especially those living in nursing homes, are disproportionately affected by chronic wounds, and effective managem...
Diabetic foot ulcers (DFUs) are a severe complication of diabetes, characterized by impaired wound healing, chronic inflammation, and tissue degradation. N-methyladenosine (mA), has emerged as a critical regulator in gene expression and cellular func...
Due to the excellent biocompatibility and adjustability, hydrogels have broadened their application in different fields, such as 3D printing, tissue engineering, drug delivery, and biosensing. However, traditional hydrogel research is confronted with...
BACKGROUND: Peripheral arterial disease (PAD) and local infections increase the risk of non-healing diabetic foot ulcers (DFU) and limb amputations but are treatable by percutaneous transluminal angioplasty (PTA), local wound care and antibiotic ther...
Wound healing is a dynamic process involving various cell types. Collecting samples from healing wounds and investigating their transcriptomics can provide deeper insights into the underlying processes. In recent years, several experiments have been ...
BACKGROUND: Machine learning (ML) has shown great potential in recognizing complex disease patterns and supporting clinical decision-making. Diabetic foot ulcers (DFUs) represent a significant multifactorial medical problem with high incidence and se...
Wound healing is a complex process that can be compromised by bacterial infections, leading to delayed healing and an increased risk of complications. The aim of this study was to design and develop a novel antibacterial peptide, Healitide-GP1, which...
Managing inflammation in diabetic chronic wounds remains a major clinical challenge, primarily due to the lack of real-time monitoring techniques. To address this issue, we developed a peptide hydrogel capable of simultaneously monitoring the inflamm...
International journal of pharmaceutics
Aug 20, 2025
Chronic wounds represent a significant healthcare challenge characterized by complex pathophysiology and poor clinical outcomes. The latest progress in smart bioelectronic systems which include biosensing capabilities alongside controlled drug delive...
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