AIMC Topic: X-Ray Microtomography

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Ensemble methods and partially-supervised learning for accurate and robust automatic murine organ segmentation.

Scientific reports
Delineation of multiple organs in murine µCT images is crucial for preclinical studies but requires manual volumetric segmentation, a tedious and time-consuming process prone to inter-observer variability. Automatic deep learning-based segmentation c...

Volumetric atlas of the rat inner ear from microCT and iDISCO+ cleared temporal bones.

PeerJ
BACKGROUND: Volumetric atlases are an invaluable tool in neuroscience and otolaryngology, greatly aiding experiment planning and surgical interventions, as well as the interpretation of experimental and clinical data. The rat is a major animal model ...

Assessing the cardioprotective effects of exercise in APOE mouse models using deep learning and photon-counting micro-CT.

PloS one
BACKGROUND: The allelic variations of the apolipoprotein E (APOE) gene play a critical role in regulating lipid metabolism and significantly impact cardiovascular disease risk (CVD). This study aimed to evaluate the impact of exercise on cardiac stru...

Enhancing synchrotron radiation micro-CT images using deep learning: an application of Noise2Inverse on bone imaging.

Journal of synchrotron radiation
In bone-imaging research, in situ synchrotron radiation micro-computed tomography (SRµCT) mechanical tests are used to investigate the mechanical properties of bone in relation to its microstructure. Low-dose computed tomography (CT) is used to prese...

A modular cage may prevent endplate damage and improve spinal deformity correction.

Clinical biomechanics (Bristol, Avon)
BACKGROUND: Anterior lumbar interbody fusion is performed to fuse pathological spinal segments, generally, with a monobloc cage inserted by impact forces. Recently developed three-part modular cages attempt to reduce the impact forces, minimize the d...

The effect of cryopreservation on enamel microcracks - A μCT analysis using a deep learning algorithm.

Cryobiology
To date, the effect of cryopreservation on microcracks in the dental enamel remains unclear. These enamel microcracks are very thin, at the limit of visibility and their segmentation is beyond the capabilities of traditional image analysis. The objec...

A robust deep learning approach for segmenting cortical and trabecular bone from 3D high resolution µCT scans of mouse bone.

Scientific reports
Recent advancements in deep learning have significantly enhanced the segmentation of high-resolution microcomputed tomography (µCT) bone scans. In this paper, we present the dual-branch attention-based hybrid network (DBAHNet), a deep learning archit...

Cell quantification at the osteochondral interface from synchrotron radiation phase contrast micro-computed tomography images using a deep learning approach.

Scientific reports
Osteochondral interface consists of two tissues: the calcified cartilage (CC) containing chondrocytes, and subchondral bone (SCB) containing osteocytes that interact with each other. In this study, we propose a new method for the three-dimensional (3...

Reconstructing 3D histological structures using machine learning (artificial intelligence) algorithms.

Pathologie (Heidelberg, Germany)
BACKGROUND: Histomorphometry is currently the gold standard for bone microarchitectural examinations. This relies on two-dimensional (2D) sections to deduce the spatial properties of structures. Micromorphometric parameters are calculated from these ...

Self-adaptive deep learning-based segmentation for universal and functional clinical and preclinical CT image analysis.

Computers in biology and medicine
BACKGROUND: Methods to monitor cardiac functioning non-invasively can accelerate preclinical and clinical research into novel treatment options for heart failure. However, manual image analysis of cardiac substructures is resource-intensive and error...