AIMC Topic: Zebrafish

Clear Filters Showing 151 to 160 of 164 articles

Swimming into the future: Machine learning in zebrafish behavioral research.

Progress in neuro-psychopharmacology & biological psychiatry
The zebrafish (Danio rerio) has emerged as a powerful organism in behavioral neuroscience, offering invaluable insights into the neural circuits and molecular pathways underlying complex behaviors. Although the knowledge of zebrafish behavioral reper...

Predicting Bioconcentration Factors of Per- and Polyfluoroalkyl Substances Using a Directed Message Passing Neural Network with Multimodal Feature Fusion.

Environmental science & technology
Amid growing concerns regarding the ecological risks posed by emerging contaminants, per- and polyfluoroalkyl substances (PFASs) present significant challenges for risk assessment due to their structural diversity and the paucity of experimental data...

An AI-driven strategy for active compounds discovery and non-destructive quality control in traditional Chinese medicine: A case of Xuefu Zhuyu Oral Liquid.

Talanta
The modernization and globalization of traditional Chinese medicine (TCM) face challenges such as unclear active compounds and inadequate quality control. Taking Xuefu Zhuyu Oral Liquid (XZOL) as an example, this study proposed an artificial intellig...

Pose estimation and tracking dataset for multi-animal behavior analysis on the China Space Station.

Scientific data
Non-contact behavioral study through intelligent image analysis is becoming increasingly vital in animal neuroscience and ethology. The shift from traditional "black box" methods to more open and intelligent approaches is driven by advances in deep l...

High-throughput genetic manipulation of multicellular organisms using a machine-vision guided embryonic microinjection robot.

Genetics
Microinjection is a technique used for transgenesis, mutagenesis, cell labeling, cryopreservation, and in vitro fertilization in multiple single and multicellular organisms. Microinjection requires specialized skills and involves rate-limiting and la...

Multiscale, multi-perspective imaging assisted robotic microinjection of 3D biological structures.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Microinjection is a widely used technique employed by biologists with applications in transgenesis, cryopreservation, mutagenesis, labeling/dye injection and in-vitro fertilization. However, microinjection is an extremely laborious manual procedure, ...

XGSEA: CROSS-species gene set enrichment analysis via domain adaptation.

Briefings in bioinformatics
MOTIVATION: Gene set enrichment analysis (GSEA) has been widely used to identify gene sets with statistically significant difference between cases and controls against a large gene set. GSEA needs both phenotype labels and expression of genes. Howeve...

The Gene Ontology resource: enriching a GOld mine.

Nucleic acids research
The Gene Ontology Consortium (GOC) provides the most comprehensive resource currently available for computable knowledge regarding the functions of genes and gene products. Here, we report the advances of the consortium over the past two years. The n...

m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome.

Nucleic acids research
N 6-Methyladenosine (m6A) is the most prevalent RNA modification on mRNAs and lncRNAs. It plays a pivotal role during various biological processes and disease pathogenesis. We present here a comprehensive knowledgebase, m6A-Atlas, for unraveling the ...

Investigating the anti-angiogenic effects of Fufang Kushen Injection in combination with cisplatin using a zebrafish model.

Pakistan journal of pharmaceutical sciences
The Traditional Chinese Medicine formula Fufang Kushen Injection (FKI) has demonstrated potential to enhance the efficacy and reduce the toxicity of the chemotherapeutic drug cisplatin. However, there is insufficient evidence to determine whether the...