Birds, bats and many insects can tuck their wings against their bodies when at rest and deploy them to power flight. Whereas birds and bats use well-developed pectoral and wing muscles, how insects control their wing deployment and retraction remains...
Advancements in optical coherence control have unlocked many cutting-edge applications, including long-haul communication, light detection and ranging (LiDAR) and optical coherence tomography. Prevailing wisdom suggests that using more coherent light...
De novo design of complex protein folds using solely computational means remains a substantial challenge. Here we use a robust deep learning pipeline to design complex folds and soluble analogues of integral membrane proteins. Unique membrane topolog...
Computational pathology has witnessed considerable progress in the development of both task-specific predictive models and task-agnostic self-supervised vision encoders. However, despite the explosive growth of generative artificial intelligence (AI)...
Exoskeletons have enormous potential to improve human locomotive performance. However, their development and broad dissemination are limited by the requirement for lengthy human tests and handcrafted control laws. Here we show an experiment-free meth...
Animals have exquisite control of their bodies, allowing them to perform a diverse range of behaviours. How such control is implemented by the brain, however, remains unclear. Advancing our understanding requires models that can relate principles of ...
The development of neural techniques has opened up new avenues for research in machine translation. Today, neural machine translation (NMT) systems can leverage highly multilingual capacities and even perform zero-shot translation, delivering promisi...
Digital pathology poses unique computational challenges, as a standard gigapixel slide may comprise tens of thousands of image tiles. Prior models have often resorted to subsampling a small portion of tiles for each slide, thus missing the important ...
The introduction of AlphaFold 2 has spurred a revolution in modelling the structure of proteins and their interactions, enabling a huge range of applications in protein modelling and design. Here we describe our AlphaFold 3 model with a substantially...
Insects constitute the most species-rich radiation of metazoa, a success that is due to the evolution of active flight. Unlike pterosaurs, birds and bats, the wings of insects did not evolve from legs, but are novel structures that are attached to th...