AI Medical Compendium Journal:
Translational psychiatry

Showing 11 to 20 of 47 articles

Developing multifactorial dementia prediction models using clinical variables from cohorts in the US and Australia.

Translational psychiatry
Existing dementia prediction models using non-neuroimaging clinical measures have been limited in their ability to identify disease. This study used machine learning to re-examine the diagnostic potential of clinical measures for dementia. Data was s...

Application of functional near-infrared spectroscopy and machine learning to predict treatment response after six months in major depressive disorder.

Translational psychiatry
Depression treatment responses vary widely among individuals. Identifying objective biomarkers with predictive accuracy for therapeutic outcomes can enhance treatment efficiency and avoid ineffective therapies. This study investigates whether functio...

Virtual reality-assisted prediction of adult ADHD based on eye tracking, EEG, actigraphy and behavioral indices: a machine learning analysis of independent training and test samples.

Translational psychiatry
Given the heterogeneous nature of attention-deficit/hyperactivity disorder (ADHD) and the absence of established biomarkers, accurate diagnosis and effective treatment remain a challenge in clinical practice. This study investigates the predictive ut...

DeepASD: a deep adversarial-regularized graph learning method for ASD diagnosis with multimodal data.

Translational psychiatry
Autism Spectrum Disorder (ASD) is a prevalent neurological condition with multiple co-occurring comorbidities that seriously affect mental health. Precisely diagnosis of ASD is crucial to intervention and rehabilitation. A single modality may not ful...

Accuracy and transportability of machine learning models for adolescent suicide prediction with longitudinal clinical records.

Translational psychiatry
Machine Learning models trained from real-world data have demonstrated promise in predicting suicide attempts in adolescents. However, their transportability, namely the performance of a model trained on one dataset and applied to different data, is ...

Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches.

Translational psychiatry
The causes of depression are complex, and the current diagnosis methods rely solely on psychiatric evaluations with no incorporation of laboratory biomarkers in clinical practices. We investigated the stability of blood DNA methylation depression sig...

Neuroimaging and natural language processing-based classification of suicidal thoughts in major depressive disorder.

Translational psychiatry
Suicide is a growing public health problem around the world. The most important risk factor for suicide is underlying psychiatric illness, especially depression. Detailed classification of suicide in patients with depression can greatly enhance perso...

Development of a differential treatment selection model for depression on consolidated and transformed clinical trial datasets.

Translational psychiatry
Major depressive disorder (MDD) is the leading cause of disability worldwide, yet treatment selection still proceeds via "trial and error". Given the varied presentation of MDD and heterogeneity of treatment response, the use of machine learning to u...

A novel blood-based epigenetic biosignature in first-episode schizophrenia patients through automated machine learning.

Translational psychiatry
Schizophrenia (SCZ) is a chronic, severe, and complex psychiatric disorder that affects all aspects of personal functioning. While SCZ has a very strong biological component, there are still no objective diagnostic tests. Lately, special attention ha...

Multimodal workflows optimally predict response to repetitive transcranial magnetic stimulation in patients with schizophrenia: a multisite machine learning analysis.

Translational psychiatry
The response variability to repetitive transcranial magnetic stimulation (rTMS) challenges the effective use of this treatment option in patients with schizophrenia. This variability may be deciphered by leveraging predictive information in structura...