When incorporating more realistic synaptic dynamics, the computational efficiency of population density methods (PDMs) declines sharply due to the increase in the dimension of master equations. To avoid such a decline, we develop an efficient PDM, te...
Fear of pain demonstrates significant prognostic value regarding the development of persistent musculoskeletal pain and disability. Its assessment often relies on self-report measures of pain-related fear by a variety of questionnaires. However, base...
The mammalian visual system consists of several anatomically distinct areas, layers, and cell types. To understand the role of these subpopulations in visual information processing, we analyzed neural signals recorded from excitatory neurons from var...
The robustness of the visual system lies in its ability to perceive degraded images. This is achieved through interacting bottom-up, recurrent, and top-down pathways that process the visual input in concordance with stored prior information. The inte...
Specialized brain structures encode spatial locations and movements, yet there is growing evidence that this information is also represented in the rodent medial prefrontal cortex (mPFC). Disambiguating such information from the encoding of other typ...
Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine dynamics is...
Most people tend to bisect horizontal lines slightly to the left of their true center (pseudoneglect) and start visual search from left-sided items. This physiological leftward spatial bias may depend on hemispheric asymmetries in the organization of...
The supraoptic nucleus (SON) is a group of neurons in the hypothalamus responsible for the synthesis and secretion of the peptide hormones vasopressin and oxytocin. Following physiological cues, such as dehydration, salt-loading and lactation, the SO...
Synapse formation analyses can be performed by imaging and quantifying fluorescent signals of synaptic markers. Traditionally, these analyses are done using simple or multiple thresholding and segmentation approaches or by labor-intensive manual anal...
Humans instantly recognize a previously seen face as "familiar." To deepen our understanding of familiarity-novelty detection, we simulated biologically plausible neural network models of generic cortical microcircuits consisting of spiking neurons w...