AIMC Topic: Aged, 80 and over
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Radiomic and proteomic signatures of body mass index on brain ageing and Alzheimer's-like patterns of brain atrophy.
EBioMedicine
May 27, 2025
BACKGROUND: The impact of high body mass index (BMI) states and associated proteomic factors on brain ageing and Alzheimer's disease (AD) remains unclear.
Heterogeneity in the association between internet use and dementia among older adults: A machine-learning analysis.
Archives of gerontology and geriatrics
May 26, 2025
BACKGROUND & AIMS: Internet use among older adults may reduce the risk of dementia, but it remains unknown how the effects vary across individuals. The aim of this study was to rigorously examine heterogeneity in the association between internet use ...
Two birds with one stone: pre-TAVI coronary CT angiography combined with FFR helps screen for coronary stenosis.
BMC medical imaging
May 26, 2025
OBJECTIVES: Since coronary artery disease (CAD) is a common comorbidity in patients with aortic valve stenosis, invasive coronary angiography (ICA) can be avoided if significant CAD can be screened with the non-invasive coronary CT angiography (cCTA)...
Humans
Machine Learning
Retrospective Studies
Male
Aortic Valve Stenosis
Predictive Value of Tests
Coronary Angiography
Coronary Artery Disease
Female
Aged
Aged, 80 and over
Sensitivity and Specificity
Computed Tomography Angiography
Coronary Stenosis
Fractional Flow Reserve, Myocardial
Transcatheter Aortic Valve Replacement
Development and validation of a predictive model for refracture risk in elderly individuals with osteoporotic vertebral compression fracture: a retrospective study in China.
Aging clinical and experimental research
May 26, 2025
BACKGROUND: The rising incidence of refractures and associated adverse outcomes among individuals with osteoporotic vertebral compression fractures has gained significant attention. Identifying refracture risk is crucial for implementing effective pr...
Characterising physical activity patterns in community-dwelling older adults using digital phenotyping: a 2-week observational study protocol.
BMJ open
May 24, 2025
INTRODUCTION: Physical activity (PA) is crucial for older adults' well-being and mitigating health risks. Encouraging active lifestyles requires a deeper understanding of the factors influencing PA, which conventional approaches often overlook by ass...
Development and validation of a hypoxemia prediction model in middle-aged and elderly outpatients undergoing painless gastroscopy.
Scientific reports
May 23, 2025
Hypoxemia is a common complication associated with anesthesia in painless gastroscopy. With the aging of the social population, the number of cases of hypoxemia among middle-aged and elderly patients is increasing. However, tools for predicting hypox...
Leveraging Digital Twins for Stratification of Patients with Breast Cancer and Treatment Optimization in Geriatric Oncology: Multivariate Clustering Analysis.
JMIR cancer
May 23, 2025
BACKGROUND: Defining optimal adjuvant therapeutic strategies for older adult patients with breast cancer remains a challenge, given that this population is often overlooked and underserved in clinical research and decision-making tools.
The value of radiomics features of white matter hyperintensities in diagnosing cognitive frailty: a study based on T2-FLAIR imaging.
BMC medical imaging
May 22, 2025
BACKGROUND: White matter hyperintensities (WMHs) are closely associated with cognitive frailty (CF). This study aims to explore the potential diagnostic value of WMHs for CF based on radiomics approaches, thereby providing a novel methodology for the...
Performance of multimodal prediction models for intracerebral hemorrhage outcomes using real-world data.
International journal of medical informatics
May 21, 2025
BACKGROUND: We aimed to develop and validate multimodal models integrating computed tomography (CT) images, text and tabular clinical data to predict poor functional outcomes and in-hospital mortality in patients with intracerebral hemorrhage (ICH). ...
Development and validation of a nomogram for differentiating immune checkpoint inhibitor-related pneumonitis from pneumonia in patients undergoing immunochemotherapy: a multicenter, real-world, retrospective study.
Frontiers in immunology
May 19, 2025
BACKGROUND: Immune Checkpoint Inhibitor-related Pneumonitis (CIP) exhibits high morbidity and mortality rates in the real world, often coexisting with pneumonia, particularly after immunochemotherapy. We aimed to develop and validate a non-invasive n...
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