AIMC Topic: Aged

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Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical features.

EBioMedicine
BACKGROUND: Ductal Carcinoma In Situ (DCIS) can progress to ipsilateral invasive breast cancer (IBC) but over 75% of DCIS lesions do not progress if untreated. Currently, DCIS that might progress to IBC cannot reliably be identified. Therefore, most ...

Detecting Tardive Dyskinesia Using Video-Based Artificial Intelligence.

The Journal of clinical psychiatry
Tardive dyskinesia (TD) is a late-onset adverse effect of dopamine receptor-blocking medications, characterized by involuntary movements primarily affecting the mouth, though other body parts may be involved. Severity of TD varies from mild to debil...

Operationalizing postmortem pathology-MRI association studies in Alzheimer's disease and related disorders with MRI-guided histology sampling.

Acta neuropathologica communications
Postmortem neuropathological examination, while the gold standard for diagnosing neurodegenerative diseases, often relies on limited regional sampling that may miss critical areas affected by Alzheimer's disease and related disorders. Ultra-high reso...

Personalized prediction of gait freezing using dynamic mode decomposition.

Scientific reports
Freezing of gait (FoG) is a common severe gait disorder in patients with advanced Parkinson's disease. The ability to predict the onset of FoG episodes early on allows for timely intervention, which is essential for improving the life quality of pati...

Improving ACS prediction in T2DM patients by addressing false records in electronic medical records using propensity score.

Scientific reports
Our study aims to improve the prediction performance of machine learning (ML) models by addressing false records (i.e., false positive, false negative, or missingness) in binary categorical variables in electronic medical records (EMRs) using propens...

MicroRNA signature predicts post operative atrial fibrillation after coronary artery bypass grafting.

Scientific reports
Early detection of atrial fibrillation (AFib) is crucial for altering its natural progression and complication profile. Traditional demographic and lifestyle factors often fail as predictors of AFib. This study investigated pre-operative, circulating...

C2 pars interarticularis length on the side of high-riding vertebral artery with implications for pars screw insertion.

Scientific reports
C2 pars interarticularis length (C2PIL) required for pars screws has not been thoroughly studied in subjects with high-riding vertebral artery (HRVA). We aimed to measure C2PIL specifically on the sides with HRVA, define short pars, optimal pars scre...

Advanced predictive modeling for enhanced mortality prediction in ICU stroke patients using clinical data.

PloS one
Background Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in intensive care u...

Machine learning models of depression in middle-aged and older adults with cardiovascular metabolic diseases.

Journal of affective disorders
BACKGROUND: The incidence of cardiovascular metabolic diseases (CMD) is increasing, and depression in CMD patients significantly impacts prognosis. Therefore, this study aimed to develop and validate a predictive model for depression in CMD patients ...