BACKGROUND: Transcription factors (TFs) play important roles in the regulation of gene expression. They can activate or block transcription of downstream genes in a manner of binding to specific genomic sequences. Therefore, motif discovery of these ...
Heart disease is a malignant threat to human health. Electrocardiogram (ECG) tests are used to help diagnose heart disease by recording the heart's activity. However, automated medical-aided diagnosis with computers usually requires a large volume of...
The Journal of international medical research
Apr 30, 2019
OBJECTIVE: Atherosclerosis (AS) is the main pathological basis of ischemic cardio-cerebrovascular diseases, and the intimal thickness (IT) of large arteries is regarded as a powerful evaluation indicator for AS. We established an effective neural net...
OBJECTIVES: To evaluate the performance of a novel three-dimensional (3D) joint convolutional and recurrent neural network (CNN-RNN) for the detection of intracranial hemorrhage (ICH) and its five subtypes (cerebral parenchymal, intraventricular, sub...
International journal of computer assisted radiology and surgery
Apr 30, 2019
PURPOSE: We address the automatic segmentation of healthy and cancerous liver tissues (parenchyma, active and necrotic parts of hepatocellular carcinoma (HCC) tumor) on multiphase CT images using a deep learning approach.
Advances in predictive analytics and machine learning supported by an ever-increasing wealth of data and processing power are transforming almost every industry. Accuracy and precision of predictive analytics have significantly increased over the pas...
Computer methods and programs in biomedicine
Apr 30, 2019
BACKGROUND AND OBJECTIVE: Automatic extraction of adverse drug effect (ADE) mentions from biomedical texts is a challenging research problem that has attracted significant attention from the pharmacovigilance and biomedical text mining communities. I...
This paper presents a framework for automatically learning shape and appearance models for medical (and certain other) images. The algorithm was developed with the aim of eventually enabling distributed privacy-preserving analysis of brain image data...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Apr 30, 2019
This paper proposes a Gaussian process-based method for trajectory learning and generation of individualized gait motions at arbitrary user-designated walking speeds, intended to be used in generating reference motions for robotic gait rehabilitation...
The performance of quantitative structure-activity relationship (QSAR) models largely depends on the relevance of the selected molecular representation used as input data matrices. This work presents a thorough comparative analysis of two main catego...
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