AIM: This study evaluates the comparative effectiveness of pathologists versus artificial intelligence (AI) algorithms in scoring PD-L1 expression in non-small cell lung carcinoma (NSCLC). Immune-checkpoint inhibitors have revolutionized NSCLC treatm...
Interdisciplinary sciences, computational life sciences
Feb 17, 2025
Increasing evidences have indicated that circular RNAs play a crucial role in the onset and progression of various diseases. However, exploring potential disease-associated circRNAs using conventional experimental techniques remains both time-intensi...
OBJECTIVE: Otitis Media (OM) - ear infection - can lead to hearing loss and associated developmental delay. There are several subgroups of OM which can be difficult to diagnose accurately, even for experienced clinicians. AI and machine learning algo...
The dynamics of neuron populations commonly evolve on low-dimensional manifolds. Thus, we need methods that learn the dynamical processes over neural manifolds to infer interpretable and consistent latent representations. We introduce a representatio...
BACKGROUND: Tuberculosis (TB) continues to pose a significant threat to global public health. Enhancing patient prognosis is essential for alleviating the disease burden.
In order to detect epileptic spikes, this paper suggests a deep learning architecture that blends 1D residual convolutional neural networks (1D-ResCNN) with a hybrid optimization strategy. The Layer-wise Adaptive Moments (LAMB) and AdamW algorithms h...
Traditional methods for diagnosing chronic kidney disease (CKD) via laboratory data may not be capable of identifying early kidney disease. Kidney biopsy is unsuitable for regular screening, and imaging tests are costly and time-consuming. Several st...
Heart Rate Variability (HRV) serves as a vital marker of stress levels, with lower HRV indicating higher stress. It measures the variation in the time between heartbeats and offers insights into health. Artificial intelligence (AI) research aims to u...
The rapid increase in the amount of available biological data together with increasing computational power and innovative new machine learning algorithms has resulted in great potential for machine learning approaches to revolutionise image analysis ...
SIGNIFICANCE: Current methods for complex conjugate removal (CCR) in frequency-domain optical coherence tomography (FD-OCT) often require additional hardware components, which increase system complexity and cost. A software-based solution would provi...
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