AIMC Topic: Amyotrophic Lateral Sclerosis
Clear Filters Showing 51 to 60 of 72 articles
String Grammar Unsupervised Possibilistic Fuzzy C-Medians for Gait Pattern Classification in Patients with Neurodegenerative Diseases.
Computational intelligence and neuroscience
Jun 13, 2018
Neurodegenerative diseases that affect serious gait abnormalities include Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington disease (HD). These diseases lead to gait rhythm distortion that can be determined by stride time ...
Multicenter validation of [F]-FDG PET and support-vector machine discriminant analysis in automatically classifying patients with amyotrophic lateral sclerosis versus controls.
Amyotrophic lateral sclerosis & frontotemporal degeneration
Jun 4, 2018
OBJECTIVE: F-Fluorodeoxyglucose (F-FDG) positron emission tomography (PET) single-center studies using support vector machine (SVM) approach to differentiate amyotrophic lateral sclerosis (ALS) from controls have shown high overall accuracy on an ind...
Artificial intelligence in neurodegenerative disease research: use of IBM Watson to identify additional RNA-binding proteins altered in amyotrophic lateral sclerosis.
Acta neuropathologica
Nov 13, 2017
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no effective treatments. Numerous RNA-binding proteins (RBPs) have been shown to be altered in ALS, with mutations in 11 RBPs causing familial forms of the disease, a...
Deep learning predictions of survival based on MRI in amyotrophic lateral sclerosis.
NeuroImage. Clinical
Oct 11, 2016
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease, with large variation in survival between patients. Currently, it remains rather difficult to predict survival based on clinical parameters alone. Here, we set out to use clin...
Design of Biomedical Robots for Phenotype Prediction Problems.
Journal of computational biology : a journal of computational molecular cell biology
Jun 27, 2016
Genomics has been used with varying degrees of success in the context of drug discovery and in defining mechanisms of action for diseases like cancer and neurodegenerative and rare diseases in the quest for orphan drugs. To improve its utility, accur...
A novel approach for analysis of altered gait variability in amyotrophic lateral sclerosis.
Medical & biological engineering & computing
Oct 30, 2015
Gait variability reflects important information for the maintenance of human beings' health. For pathological populations, changes in gait variability signal the presence of abnormal motor control strategies. Quantitative analysis of the altered gait...
Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex.
Neurobiology of disease
Dec 10, 2014
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and ultimately fatal neurodegenerative disease, caused by the loss of motor neurons in the brain and spinal cord. Although 10% of ALS cases are familial (FALS), the majority are sporadic (S...
Exploring oculomotor challenges in amyotrophic lateral sclerosis: a comprehensive review.
Amyotrophic lateral sclerosis & frontotemporal degeneration
Aug 1, 2025
Traditionally understood as a motor neuron disease, amyotrophic lateral sclerosis (ALS) is now recognized to involve broader neurodegenerative processes, including the oculomotor system. This narrative review summarizes current evidence on oculomotor...
Deep learning analyses of splicing variants identify the link of PCP4 with amyotrophic lateral sclerosis.
Brain : a journal of neurology
Jul 7, 2025
Amyotrophic lateral sclerosis (ALS) is a severe motor neuron disease, with most sporadic cases lacking clear genetic causes. Abnormal pre-mRNA splicing is a fundamental mechanism in neurodegenerative diseases. For example, TAR DNA-binding protein 43 ...
Artificial intelligence models using F-wave responses predict amyotrophic lateral sclerosis.
Brain : a journal of neurology
Jul 7, 2025
Nerve conduction F-wave studies contain crucial information about subclinical motor dysfunction that can be used to diagnose patients with amyotrophic lateral sclerosis (ALS). However, F-wave responses are highly variable in morphology, making wavefo...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31964
- Neural Networks, Computer 30201
- Algorithms 27375
- Deep Learning 26880
- Artificial Intelligence 24818
- Robotics 13382
- Image Processing, Computer-Assisted 9730
- Retrospective Studies 9328
- Magnetic Resonance Imaging 6341
- Reproducibility of Results 5670
- Tomography, X-Ray Computed 4863
- Support Vector Machine 4762
- Computational Biology 4328
- Brain 4125
- Computer Simulation 3932
Recent Journals
- Scientific reports 6689
- Sensors (Basel, Switzerland) 4794
- PloS one 4186
- Neural networks : the official journal of the International Neural Network Society 3026
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1915
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1378
- IEEE journal of biomedical and health informatics 1167
- Journal of chemical information and modeling 1059
- Nature communications 1029
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 872
- Journal of medical Internet research 853
- Briefings in bioinformatics 853