AIMC Topic: Angiogenesis Inhibitors
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First-line combination therapy of immunotherapy plus anti-angiogenic drug for thoracic SMARCA4-deficient undifferentiated tumors in AIDS: a case report and review of the literature.
Frontiers in immunology
Jan 9, 2025
BACKGROUND: Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UT) exhibit a notably aggressive phenotype, which is associated with poor patient survival outcomes. These tumors are generally resistant to conventional cytotoxic chemotherapy, ...
Retinal fluid quantification using a novel deep learning algorithm in patients treated with faricimab in the TRUCKEE study.
Eye (London, England)
Dec 11, 2024
BACKGROUND: Investigate retinal fluid changes via a novel deep-learning algorithm in real-world patients receiving faricimab for the treatment of neovascular age-related macular degeneration (nAMD).
Machine learning identifies immune-based biomarkers that predict efficacy of anti-angiogenesis-based therapies in advanced lung cancer.
International immunopharmacology
Nov 17, 2024
BACKGROUND: The anti-angiogenic drugs showed remarkable efficacy in the treatment of lung cancer. Nonetheless, the potential roles of the intra-tumoral immune cell abundances and peripheral blood immunological features in prognosis prediction of pati...
Anti-VEGF treatment outcome prediction based on optical coherence tomography images in neovascular age-related macular degeneration using a deep neural network.
Scientific reports
Nov 16, 2024
Age-related macular degeneration (AMD) is a major cause of blindness in developed countries, and the number of affected patients is increasing worldwide. Intravitreal injections of anti-vascular endothelial growth factor (VEGF) are the standard thera...
Artificial intelligence-based analysis of retinal fluid volume dynamics in neovascular age-related macular degeneration and association with vision and atrophy.
Eye (London, England)
Oct 15, 2024
BACKGROUND/OBJECTIVES: To characterise morphological changes in neovascular age-related macular degeneration (nAMD) during anti-angiogenic therapy and explore relationships with best-corrected visual acuity (BCVA) and development of macular atrophy (...
Prediction of treatment outcome for branch retinal vein occlusion using convolutional neural network-based retinal fluorescein angiography.
Scientific reports
Aug 28, 2024
Deep learning techniques were used in ophthalmology to develop artificial intelligence (AI) models for predicting the short-term effectiveness of anti-VEGF therapy in patients with macular edema secondary to branch retinal vein occlusion (BRVO-ME). 1...
Deep reinforcement learning control of combined chemotherapy and anti-angiogenic drug delivery for cancerous tumor treatment.
Computers in biology and medicine
Aug 23, 2024
By virtue of the chronic and dangerous nature of cancer, researchers have explored various approaches to managing the abnormal cell growth associated with this disease using novel treatment methods. This study introduces a control system based on nor...
Linking disease activity with optical coherence tomography angiography in neovascular age related macular degeneration using artificial intelligence.
Scientific reports
Aug 20, 2024
To investigate quantitative associations between AI-assessed disease activity and optical coherence tomography angiography (OCTA)-derived parameters in patients with neovascular age-related macular degeneration (nAMD) undergoing anti-VEGF therapy. OC...
Improved prediction of anti-angiogenic peptides based on machine learning models and comprehensive features from peptide sequences.
Scientific reports
Jun 22, 2024
Angiogenesis is a key process for the proliferation and metastatic spread of cancer cells. Anti-angiogenic peptides (AAPs), with the capability of inhibiting angiogenesis, are promising candidates in cancer treatment. We propose AAPL, a sequence-base...
Approved AI-based fluid monitoring to identify morphological and functional treatment outcomes in neovascular age-related macular degeneration in real-world routine.
The British journal of ophthalmology
Jun 20, 2024
AIM: To predict antivascular endothelial growth factor (VEGF) treatment requirements, visual acuity and morphological outcomes in neovascular age-related macular degeneration (nAMD) using fluid quantification by artificial intelligence (AI) in a real...
Ranibizumab
Wet Macular Degeneration
Subretinal Fluid
Retrospective Studies
Female
Aged
Aged, 80 and over
Visual Acuity
Male
Humans
Tomography, Optical Coherence
Angiogenesis Inhibitors
Artificial Intelligence
Vascular Endothelial Growth Factor A
Treatment Outcome
Intravitreal Injections
Follow-Up Studies
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