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Imaging-guided bioresorbable acoustic hydrogel microrobots.
Science robotics
Dec 11, 2024
Micro- and nanorobots excel in navigating the intricate and often inaccessible areas of the human body, offering immense potential for applications such as disease diagnosis, precision drug delivery, detoxification, and minimally invasive surgery. De...
Linsitinib inhibits proliferation and induces apoptosis of both IGF-1R and TSH-R expressing cells.
Frontiers in immunology
Dec 11, 2024
BACKGROUND: The insulin-like growth factor 1 receptor (IGF-1R) and the thyrotropin receptor (TSH-R) are expressed on orbital cells and thyrocytes. These receptors are targeted in autoimmune-induced thyroid eye disease (TED). Effective therapeutic tre...
Integration of bulk/scRNA-seq and multiple machine learning algorithms identifies PIM1 as a biomarker associated with cuproptosis and ferroptosis in abdominal aortic aneurysm.
Frontiers in immunology
Dec 11, 2024
BACKGROUND: Abdominal aortic aneurysm (AAA) is a serious life-threatening vascular disease, and its ferroptosis/cuproptosis markers have not yet been characterized. This study was aiming to identify markers associated with ferroptosis/cuproptosis in ...
AI-based coral species discrimination: A case study of the Siderastrea Atlantic Complex.
PloS one
Dec 11, 2024
Species delimitation in hard corals remains controversial even after 250+ years of taxonomy. Confusing taxonomy in Scleractinia is not the result of sloppy work: clear boundaries are hard to draw because most diagnostic characters are quantitative an...
Enhancing automatic sleep stage classification with cerebellar EEG and machine learning techniques.
Computers in biology and medicine
Dec 10, 2024
Sleep disorders have become a significant health concern in modern society. To investigate and diagnose sleep disorders, sleep analysis has emerged as the primary research method. Conventional polysomnography primarily relies on cerebral electroencep...
Machine learning models for quantitatively prediction of toxicity in macrophages induced by metal oxide nanoparticles.
Chemosphere
Dec 10, 2024
As nanotechnology advances, metal oxide nanoparticles (MeONPs) increasingly come into contact with humans. The inhaled MeONPs cannot be effectively cleared by cilia or lung mucus. In the last decade, potential immune toxicity arising from exposure to...
Progress of AI assisted synthesis of polysaccharides-based hydrogel and their applications in biomedical field.
International journal of biological macromolecules
Dec 10, 2024
Polymeric hydrogels, characterized by their highly hydrophilic three-dimensional network structures, boast exceptional physical and chemical properties alongside high biocompatibility and biodegradability. These attributes make them indispensable in ...
QUAIDE - Quality assessment of AI preclinical studies in diagnostic endoscopy.
Gut
Dec 10, 2024
Artificial intelligence (AI) holds significant potential for enhancing quality of gastrointestinal (GI) endoscopy, but the adoption of AI in clinical practice is hampered by the lack of rigorous standardisation and development methodology ensuring ge...
Reproductive performance of Channa striata in wetland ecosystems: a fuzzy logic approach to water quality and eco-climatic factors for long-term sustainable management and aquaculture advancement.
Environmental science and pollution research international
Dec 10, 2024
The striped snakehead, Channa striata, is commercially and nutritionally important due to its medicinal properties, such as wound healing and antimicrobial abilities. This study investigated the reproductive biology of C. striata in relation to hydro...
Machine Learning-Assisted High-Throughput Screening for Anti-MRSA Compounds.
IEEE/ACM transactions on computational biology and bioinformatics
Dec 10, 2024
BACKGROUND: Antimicrobial resistance is a major public health threat, and new agents are needed. Computational approaches have been proposed to reduce the cost and time needed for compound screening.
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