Enterocytozoon hepatopenaei (EHP), causing hepatopancreatic microsporidiosis (HPM), significantly impacts Litopenaeus vannamei, leading to economic losses. Using bioinformatics and machine learning, this study characterized EHP infection stages and h...
Lung adenocarcinoma (LUAD) constitutes a major cause of cancer-related fatalities worldwide. Early identification of malignant pulmonary nodules constitutes the most effective approach to reducing the mortality of LUAD. Despite the wide application o...
ETHNOPHARMACOLOGICAL RELEVANCE: Various parts of Prunus persica (L.) Batsch (peach) exhibit medicinal properties and are utilized in traditional Chinese medicine (TCM) for therapeutic purposes. Notably, the root of P. persica, referred to as "taoshug...
Toxicon : official journal of the International Society on Toxinology
Apr 3, 2025
Envenomation by scorpion stings is a serious public health problem in tropical regions of the world. In Brazil's Northern region, there has been a significant increase in cases over the last decade, accompanied by a rise in the fatality rate. Climate...
Sandflies are vectors for several tropical diseases such as leishmaniasis, bartonellosis, and sandfly fever. Moreover, sandflies exhibit species-specificity in transmitting particular pathogen species, with females being responsible for disease trans...
The electrical penetration graph (EPG) is a well-known technique that provides insights into the feeding behavior of insects with piercing-sucking mouthparts, mostly hemipterans. Since its inception in the 1960s, EPG has become indispensable in study...
The burgeoning field of aquaculture has become a pivotal contributor to global food security and economic growth, presently surpassing capture fisheries in aquatic animal production as evidenced by recent statistics. However, the dense fish populatio...
Prenatal brain development is particularly sensitive to chemicals that can disrupt synapse formation and cause neurodevelopmental disorders. In most cases, such chemicals increase cellular oxidative stress. For example, prenatal exposure to the anti-...
Targeting ubiquitin E3 ligases is therapeutically attractive; however, the absence of an active-site pocket impedes computational approaches for identifying inhibitors. In a large, unbiased biochemical screen, we discover inhibitors that bind a crypt...
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