AIMC Topic: Animals

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Machine learning identification of tinnitus-related features in auditory peripheral spontaneous activity in a guinea pig noise-induced tinnitus model.

Hearing research Jul 16, 2025
OBJECTIVES: Tinnitus affects millions globally, yet its clinical assessment relies on subjective reports, limiting diagnostic accuracy and treatment development. This study aimed to identify objective, tinnitus-related features within ensemble sponta...
Male Disease Models, Animal Noise Machine Learning Female Animals Behavior, Animal Acoustic Stimulation Electric Stimulation Cochlea Prepulse Inhibition Guinea Pigs Reflex, Startle Signal Processing, Computer-Assisted Tinnitus
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Monitoring of milking routines for dairy cows using a computer vision system: A diagnostic accuracy study.

Journal of dairy science Jul 16, 2025
The primary objective was to assess the performance of a computer vision system for the detection of reattachment and manual removal of the milking unit, as well as the assessment of the preparation lag time of the milking routine. The secondary obje...
Dairying Female Cattle Animals Lactation Milk
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Leveraging unsupervised machine learning techniques for detecting outliers in the daily milk yield data of dairy cows.

Journal of dairy science Jul 16, 2025
The lactation curve is essential for developing effective feeding plans, optimizing breeding, and strategizing milk production for dairy farms. However, health disorders, as well as external factors such as heat stress, dietary changes, and certain m...
Machine Learning Female Lactation Milk Dairying Animals Cattle Unsupervised Machine Learning
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Roadmap for Commercial Nanomedicine Development: Integrating Quality by Design Principles with Pharmaceutical Nanotechnology.

Molecular pharmaceutics Jul 16, 2025
Integrating Quality by Design (QbD) principles into nanomedicine development marks a paradigm shift from traditional empirical approaches to more systematic risk-based strategies. This review explores the application of QbD in pharmaceutical nanotech...
Animals Nanoparticles Drug Development Nanotechnology Liposomes Nanomedicine Humans Drug Delivery Systems
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Association of artificial intelligence-predicted milk yield residuals to behavioral patterns and transition success in multiparous dairy cows.

Journal of dairy science Jul 16, 2025
Data-driven health monitoring based on milk yield has shown potential to identify health-perturbing events during the transition period. As a proof of principle, we explored the association between the cow's residual milk yield, that is, the differen...
Milk Dairying Behavior, Animal Cattle Lactation Artificial Intelligence Pregnancy Female Animals
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Machine Learning-Based Screening of Cosmetic Ingredients Identifies Vat Blue 6 as a Thyroid Hormone Receptor β Disruptor.

Environmental science & technology Jul 16, 2025
Thyroid disorders are among the most prevalent endocrine conditions worldwide, exhibiting a rising incidence and disproportionately affecting women. In this study, we hypothesized that cosmetics may contain previously unidentified thyroid-disrupting ...
Endocrine Disruptors Thyroid Hormone Receptors beta Machine Learning Animals Female Mice Cosmetics
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Tetanus-driven biohybrid multijoint robots powered by muscle rings with enhanced contractile force.

Science advances Jul 16, 2025
Biohybrid actuators using muscle rings have been limited to twitching movements and are unsuitable for sustained contractile force applications. In this study, we developed muscle rings capable of generating high contractile forces under tetanus stim...
Myoblasts Muscle Contraction Tetanus Mice Muscle, Skeletal Animals Robotics
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A forward-engineered, muscle-driven soft robotic swimmer.

Science advances Jul 16, 2025
The field of biohybrid robotics focuses on using biological actuators to study the emergent properties of tissues and the locomotion of living organisms. On the basis of models of swimming at small size scales, we designed and fabricated a muscle-pow...
Biomechanical Phenomena Animals Robotics Motor Neurons Swimming Muscle Contraction Muscles
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Innovative organ-on-a-chip platforms for exploring tumorigenesis and therapy in head and neck cancer.

Journal of translational medicine Jul 16, 2025
BACKGROUND: Head and neck cancer (HNC) presents significant research challenges due to the complexity of its tumor microenvironment (TME) and the heterogeneity across different cancer subtypes. Recent advancements in three-dimensional (3D) culture mo...
Animals Lab-On-A-Chip Devices Microphysiological Systems Humans Spheroids, Cellular Head and Neck Neoplasms Organoids Tumor Microenvironment Carcinogenesis
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Exploration of Predictive Potential of AI-enabled Portable System in Anticancer Drug Delivery: A Comparative Study with Modified Gompertz like Biphasic Response Model.

AAPS PharmSciTech Jul 16, 2025
Mathematical models are conventionally used to understand the of tumor behaviors, but they generally lack in precisely correlating drug efficacy with tumor response. Artificial intelligence (AI) has forged a new avenue in cancer management, but requi...
Breast Neoplasms Drug Delivery Systems Animals Algorithms Female Docetaxel Antineoplastic Agents Nanoparticles Humans Cell Line, Tumor Lipids Artificial Intelligence Mice Models, Biological
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