Sleep-wake states bidirectionally interact with epilepsy and seizures, but the mechanisms are unknown. A barrier to comprehensive characterization and the study of mechanisms has been the difficulty of annotating large chronic recording datasets. To ...
We developed GlyTrait, a Python-based framework designed to enhance Glycomics analysis through the innovative calculation and interpretation of derived traits from -glycome data. Glycomics research often grapples with the interpretability and biologi...
Recent advances in single-cell multi-omics technologies have revolutionized cellular analysis, enabling comprehensive exploration of cellular heterogeneity, developmental trajectories, and disease mechanisms at unprecedented resolution. Foundation mo...
Traditional fish classification systems suffer from limited training data and imbalanced datasets, particularly for rare or morphologically complex species. This paper presents a novel Generative Adversarial Network architecture that integrates adapt...
Species Distribution Models (SDMs) are widely used in ecology to analyze historical and future patterns of marine species distributions. Given the growing impact of climate change, predicting potential shifts in species ranges has become a key challe...
BACKGROUND: Cholangiocarcinoma (CCA) is a deadly cancer often detected late. Current diagnostic methods, such as ultrasound and invasive biopsies, have limitations; there is a critical need for a rapid, minimally invasive and effective strategy for t...
Bovine respiratory disease (BRD) is a multifactorial disease of dairy and beef cattle that involves complex interactions with the host immune system. In the current study, a comprehensive meta-analysis was performed using a P-value combination approa...
Journal of controlled release : official journal of the Controlled Release Society
Oct 25, 2025
Ionic liquids (ILs) have emerged as a transformative platform in drug delivery, overcoming key limitations of conventional systems such as poor drug solubility, low bioavailability, and inadequate targeting. Through rational cation-anion engineering,...
Single-cell RNA sequencing (scRNA-seq) and its integration with multi-omics technologies such as epigenomics and spatial transcriptomics are revolutionizing our traditional understanding of cellular heterogeneity and the microenvironment in the nervo...
Biochemical and biophysical research communications
Oct 24, 2025
BACKGROUND: Aortic valve stenosis with coronary artery disease (AS-CAD) represents a common yet complex cardiovascular comorbidity, characterized by multifactorial pathogenesis and a lack of specific serum biomarkers. These limitations hinder early d...
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