AIMC Topic: Animals

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Using a deep learning prior for accelerating hyperpolarized C MRSI on synthetic cancer datasets.

Magnetic resonance in medicine
PURPOSE: We aimed to incorporate a deep learning prior with k-space data fidelity for accelerating hyperpolarized carbon-13 MRSI, demonstrated on synthetic cancer datasets.

A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors.

Nature cancer
Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6is) have revolutionized breast cancer therapy. However, <50% of patients have an objective response, and nearly all patients develop resistance during therapy. To elucidate the underlying mechanisms, ...

Unsupervised learning of perceptual feature combinations.

PLoS computational biology
In many situations it is behaviorally relevant for an animal to respond to co-occurrences of perceptual, possibly polymodal features, while these features alone may have no importance. Thus, it is crucial for animals to learn such feature combination...

A new strategy for groundwater level prediction using a hybrid deep learning model under Ecological Water Replenishment.

Environmental science and pollution research international
Accurate prediction of the groundwater level (GWL) is crucial for sustainable groundwater resource management. Ecological water replenishment (EWR) involves artificially diverting water to replenish the ecological flow and water resources of both sur...

Gasless transvaginal natural orifice transluminal endoscopic surgery for hysterectomy and salpingectomy on a robot platform with flexible devices in a porcine model.

Scientific reports
In this report, we described a new technique of gasless V-NOTES for hysterectomy and salpingectomy on a robotic platform with flexible devices in a porcine model. As a result, the gynecological procedures were successfully completed. The total operat...

Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides.

Journal of advanced research
INTRODUCTION: Antimicrobial peptides (AMPs) are valuable alternatives to traditional antibiotics, possess a variety of potent biological activities and exhibit immunomodulatory effects that alleviate difficult-to-treat infections. Clarifying the stru...

Deep Learning for Face Detection and Pain Assessment in Japanese macaques ().

Journal of the American Association for Laboratory Animal Science : JAALAS
Facial expressions have increasingly been used to assess emotional states in mammals. The recognition of pain in research animals is essential for their well-being and leads to more reliable research outcomes. Automating this process could contribute...

Design and utilisation of a novel, high-fidelity, low-cost, hybrid-tissue simulation model to facilitate training in robot-assisted partial nephrectomy.

Journal of robotic surgery
Robot-assisted partial nephrectomy (RAPN) has rapidly evolved as the standard of care for appropriately selected renal tumours, offering key patient benefits over radical nephrectomy or open surgical approaches. Accordingly, RAPN is a key competency ...

Tracking mosquito-borne diseases via social media: a machine learning approach to topic modelling and sentiment analysis.

PeerJ
Mosquito-borne diseases (MBDs) are a major threat worldwide, and public consultation on these diseases is critical to disease control decision-making. However, traditional public surveys are time-consuming and labor-intensive and do not allow for tim...

Perspectives on label-free microscopy of heterogeneous and dynamic biological systems.

Journal of biomedical optics
SIGNIFICANCE: Advancements in label-free microscopy could provide real-time, non-invasive imaging with unique sources of contrast and automated standardized analysis to characterize heterogeneous and dynamic biological processes. These tools would ov...