AIMC Topic: Animals

Clear Filters Showing 521 to 530 of 8866 articles

Multiple model visual feature embedding and selection method for an efficient pest classification supporting precision agriculture.

Scientific reports
Agriculture 5.0 is a principal economic activity in the world with major workforce dependent crops cultivation. An automated system for crops field insect pest identification can help decrease labour, while also improving the speed and precision in c...

Recent progress and perspective of magnetic miniature soft robot with multimodal locomotion.

Bioinspiration & biomimetics
Multimodal miniature soft robots, with their higher movement flexibility and environmental adaptability, represent a crucial direction for the future development of soft robots. Magnetic-driven robots, owing to their advantages such as excellent remo...

Integrated single-cell and clinical transcriptomic analysis identifies blunted glycolytic activation as a hallmark of maladaptive repair in renal ischemia-reperfusion.

Renal failure
Acute kidney injury (AKI) is a common and increases risk of chronic kidney disease (CKD). While mitochondrial dysfunction drives maladaptive repair, the role of glycolysis in renal recovery remains unclear. Here, we integrated single-cell transcripto...

Adipocyte-selective mRNA lipid nanoparticles for cell programming with machine learning analysis.

Journal of controlled release : official journal of the Controlled Release Society
Adipose tissue plays a crucial role in energy metabolism and endocrine signaling. White adipose tissue (WAT), in particular, is a compelling target for therapeutic interventions in metabolic diseases due to its secretory capacity and abundance. Gene ...

Perivascular inflammation in the progression of aortic aneurysms in Marfan syndrome.

JCI insight
Inflammation plays important roles in the pathogenesis of vascular diseases. We here show the involvement of perivascular inflammation in aortic dilatation of Marfan syndrome (MFS). In the aorta of patients with MFS and Fbn1C1041G/+ mice, macrophages...

Phenotypic Screening for Targeted Protein Degradation: Strategies, Challenges, and Emerging Opportunities.

Journal of medicinal chemistry
Phenotypic screening is undergoing a resurgence in the field of targeted protein degradation as a powerful complement to target-based approaches, which are often constrained by requirements for detailed structural and ligand-binding information. Phen...

Immune metabolic changes identify causal candidate genes and enable diagnostic frameworks in MAFLD.

Scientific reports
Metabolic dysfunction-associated fatty liver disease (MAFLD), a global epidemic affecting 25% of adults, is driven by immune-metabolic dysregulation, yet the causal mechanisms linking immune cell-specific gene perturbations to disease progression rem...

Exploring the role of oxidative stress in retinal vein occlusion: an updated and comprehensive review on the pathophysiology and treatment perspectives.

International ophthalmology
INTRODUCTION: Retinal vein occlusion (RVO) represents a prevalent cause of vision impairment within retinal vascular diseases. Although hypoperfusion and inflammation are recognized pathogenic contributors, emerging evidence highlights oxidative stre...

Human gut microbiota-derived antimicrobials against Salmonella Typhi: diversity, mechanisms, and therapeutic potential.

Archives of microbiology
Salmonella enterica serovar Typhi (S. Typhi) is a strictly human-restricted Gram-negative pathogen and the causative agent of typhoid fever, a major global health concern. Current treatment relies heavily on antibiotics, however, the rapid emergence ...

DeePosit, an AI-based tool for detecting mouse urine and fecal depositions from thermal video clips of behavioral experiments.

eLife
In many mammals, including rodents, social interactions are often accompanied by active urination (micturition), which is considered a mechanism for spatial scent marking. Urine and fecal deposits contain a variety of chemosensory signals that convey...