AIMC Topic: Animals

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DeTerm: Software for automatic detection of neuronal dendritic branch terminals via an artificial neural network.

Genes to cells : devoted to molecular & cellular mechanisms
Dendrites of neurons receive and process synaptic or sensory inputs. The Drosophila class IV dendritic arborization (da) neuron is an established model system to explore molecular mechanisms of dendrite morphogenesis. The total number of dendritic br...

MHCSeqNet: a deep neural network model for universal MHC binding prediction.

BMC bioinformatics
BACKGROUND: Immunotherapy is an emerging approach in cancer treatment that activates the host immune system to destroy cancer cells expressing unique peptide signatures (neoepitopes). Administrations of cancer-specific neoepitopes in the form of synt...

Biotechnology, Big Data and Artificial Intelligence.

Biotechnology journal
Developments in biotechnology are increasingly dependent on the extensive use of big data, generated by modern high-throughput instrumentation technologies, and stored in thousands of databases, public and private. Future developments in this area de...

Spatiotemporal discrimination in attractor networks with short-term synaptic plasticity.

Journal of computational neuroscience
We demonstrate that a randomly connected attractor network with dynamic synapses can discriminate between similar sequences containing multiple stimuli suggesting such networks provide a general basis for neural computations in the brain. The network...

Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning.

Nature methods
In mass-spectrometry-based proteomics, the identification and quantification of peptides and proteins heavily rely on sequence database searching or spectral library matching. The lack of accurate predictive models for fragment ion intensities impair...

Multiclass Classifier for P-Glycoprotein Substrates, Inhibitors, and Non-Active Compounds.

Molecules (Basel, Switzerland)
P-glycoprotein (P-gp) is a transmembrane protein that actively transports a wide variety of chemically diverse compounds out of the cell. It is highly associated with the ADMET (absorption, distribution, metabolism, excretion and toxicity) properties...

Exploratory Gene Ontology Analysis with Interactive Visualization.

Scientific reports
The Gene Ontology (GO) is a central resource for functional-genomics research. Scientists rely on the functional annotations in the GO for hypothesis generation and couple it with high-throughput biological data to enhance interpretation of results. ...

A force-measuring and behaviour-recording system consisting of 24 individual 3D force plates for the study of single limb forces in climbing animals on a quasi-cylindrical tower.

Bioinspiration & biomimetics
This study describes the design of a new force measuring array with a quasi-cylindrical surface for measuring the 3D ground reaction forces of animals climbing on a surface with high curvature. This force-measuring array was assembled from 24 individ...

Instant White Rice with Pigmented Giant Embryonic Rice Improves Glucose Metabolism and Inhibits Oxidative Stress in High-Fat Diet-Fed Mice.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
The effects of instant cooked rice made from a combination of white rice and pigmented giant embryonic Keunnunjami rice, in comparison with those of instant regular white or brown rice and instant non-pigmented giant embryonic brown rice, on the gluc...

DP-BINDER: machine learning model for prediction of DNA-binding proteins by fusing evolutionary and physicochemical information.

Journal of computer-aided molecular design
DNA-binding proteins (DBPs) participate in various biological processes including DNA replication, recombination, and repair. In the human genome, about 6-7% of these proteins are utilized for genes encoding. DBPs shape the DNA into a compact structu...