Fluorescence lifetime imaging microscopy (FLIM) has been widely used as an essential multiplexing and sensing tool in frontier fields such as materials science and life sciences. However, the accuracy of lifetime estimation is compromised by limited ...
Translational vision science & technology
Jun 2, 2025
PURPOSE: The purpose of this study was to assess the utility of artificial intelligence (AI) assisted analysis of anterior segment optical coherence tomography (AS-OCT) imaging of the device-cornea joint in predicting outcomes of an intrastromal synt...
Translational vision science & technology
Jun 2, 2025
PURPOSE: Quantifying vascular leakage in fundus fluorescein angiography (FFA) is a critical endpoint in preclinical models of diseases such as neovascular age-related macular degeneration, retinopathy of prematurity, and diabetic retinopathy. Traditi...
Adeno-associated virus (AAV) is a non-enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gen...
Organoids, 3D cellular models derived from stem cells, have revolutionized drug testing by providing human-relevant systems for modeling diseases and testing drug efficacy. Unlike traditional 2D cell cultures or animal models, organoids closely resem...
The Journal of the Acoustical Society of America
Jun 1, 2025
An automatic detector for identifying the clicks and pulsed calls of Pacific white-sided dolphins (Lagenorhynchus obliquidens) was developed using a convolutional neural network architecture for passive acoustic monitoring, particularly in the areas ...
American journal of biological anthropology
Jun 1, 2025
OBJECTIVES: The morphology of the hominoid distal femoral metaphyseal surface has been demonstrated to reflect locomotor behavior throughout ontogeny. Here, we quantify metaphyseal surface morphology to evaluate its predictive relationship to locomot...
Neural networks are responsible for processing sensory stimuli and driving the synaptic activity required for brain function and behavior. This computational capacity is expensive and requires a steady supply of energy and building blocks to operate....
With artificial intelligence becoming increasingly embedded in society, some are questioning whether it could also be used to support the diagnosis and management of parasitic disease.
International journal of biological macromolecules
Jun 1, 2025
Cysteine cathepsins have been discovered to be substantially expressed in multiple types of cancer. They play a key role in the progression and growth of these cancers, rendering them appealing targets for nanoscale delivery and noninvasive diagnosti...
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