AIMC Topic: Anti-Bacterial Agents

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Machine learning: novel bioinformatics approaches for combating antimicrobial resistance.

Current opinion in infectious diseases
PURPOSE OF REVIEW: Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning in addressing AMR is in its infancy but has made promising steps. We reviewed the current literatur...

Single and joint antibacterial activity of aqueous garlic extract and Manuka honey on extended-spectrum beta-lactamase-producing Escherichia coli.

Transactions of the Royal Society of Tropical Medicine and Hygiene
BACKGROUND: Multidrug resistance and recent technological advances have renewed interest in natural product drug discovery from ancient remedies such as Allium sativum (garlic) and honey. This study assessed antibacterial activity of aqueous garlic e...

Community-Acquired Pneumonia Case Validation in an Anonymized Electronic Medical Record-Linked Expert System.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
An electronic anonymized patient portal analysis using radiographic reports and admission and discharge diagnoses had sensitivity, specificity, positive predictive value, and negative predictive value of 84.7%, 78.2%, 75%, and 87%, respectively, for ...

MICROTOX TEST AS A TOOL TO ASSESS ANTIMICROBIAL PROPERTIES OF HERBAL INFUSIONS USED IN URINARY TRACT INFECTIONS.

Acta poloniae pharmaceutica
Herbs can be used preventatively, to aid treatment and to ease the symptoms of urinary tract infections (UTIs). Traditional medicine uses herbal infusions such as: lingonberry leaf (Vitis idaeae folium), birch leaf (Betulaefolium) wild thyme extract ...

RESEARCH ON EXTRACTION TECHNOLOGY, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF ETHANOL EXTRACT FROM LEAVES OF ABUTILON THEOPHRASTI MEDIC.

Acta poloniae pharmaceutica
This paper described the extraction procedure and determination method for the total flavonoids in ethanol extract from the leaves of Abutilon theophrasti Medic., and evaluated antibacterial and antioxidant activity. Maximum extraction yield was achi...

[Antibacterial activity of silver nanoparticles against multiple drug resistant strains].

Wei sheng wu xue bao = Acta microbiologica Sinica
OBJECTIVE: The objective of the study was to assess the antimicrobial activity of silver nanoparticles (AgNPs) against multiple drug resistant strains.

A simplified chart for determining the initial loading dose of teicoplanin in critically ill patients.

Die Pharmazie
AIM OF THE STUDY: A simplified chart to determine the initial loading dose of teicoplanin (TEIC chart) for achieving the target trough concentration was developed. The aim of the present study was to evaluate the usefulness of this chart in criticall...

Effects of Caesalpinia sappan on pathogenic bacteria causing dental caries and gingivitis.

Drug discoveries & therapeutics
The present study explores antimicrobial activities of Caesalpinia sappan extracts against three strains of oral pathogenic bacteria; Streptococcus mutans DMST9567 (Smu9), Streptococcus mutans DMST41283 (Smu4), and Streptococcus intermedius DMST42700...

Chemical Composition and Antibacterial Activity of the Essential Oil of Vitex agnus-castus L. (Lamiaceae).

Anais da Academia Brasileira de Ciencias
Abnormal multiplication of oral bacteria causes dental caries and dental plaque. These diseases continue to be major public health concerns worldwide, mainly in developing countries. In this study, the chemical composition and antimicrobial activity ...

Development of a Web-Enabled SVR-Based Machine Learning Platform and its Application on Modeling Transgene Expression Activity of Aminoglycoside-Derived Polycations.

Combinatorial chemistry & high throughput screening
OBJECTIVE: Support Vector Regression (SVR) has become increasingly popular in cheminformatics modeling. As a result, SVR-based machine learning algorithms, including Fuzzy-SVR and Least Square-SVR (LS-SVR) have been developed and applied in various r...