The excessive use of tetracyclines (TCs) poses a significant threat to human health, necessitating the development of convenient, rapid, and intelligent detection methods for monitoring TCs residues in food products. In this work, we present a hetero...
Pervasive antibiotic pollution in water environments has emerged as a serious threat to global ecosystem functions and public health. While wetland expansion─including protection, restoration, and construction, is widely promoted for sustainable wate...
Rural domestic sewage has emerged as an important reservoir of antibiotic resistance genes (ARGs) under rapid urbanization, while the national-scale geographical patterns and risks of ARGs remaining unclear. We investigated ARG pollution in rural dom...
This research proposes a machine learning controlled method for removing the antibiotic oxytetracycline (OTC) from liquids through the use of nanostructured cupric oxide (CuO) nanoparticles. These nanoparticles are attached to magnetic chitosan/algin...
The uncontrolled use of antibiotics poses a significant threat to human health and ecosystems. Accurate differentiation and trace detection of fluoroquinolone antibiotics (FQs) in foods are imperative. Fluorine-doped carbon quantum dots chelated with...
BACKGROUND: The current Surviving Sepsis Campaign (SSC) guidelines provide recommendations on timing of administering antibiotics in sepsis patients based on probability of sepsis and presence of shock. However, there have been minimal efforts to str...
The challenge of assessing intracellular accumulation represents a major hurdle to the discovery of new antibiotics with Gram-negative activity. To address this, a high-throughput assay was developed to measure compound uptake and retention in Escher...
Helicobacter pylori (H. pylori) is the most common carcinogenic pathogen globally and the leading cause of gastric cancer. Here, we develop a reinforcement learning-based AI Clinician system to personalise treatment selection and evaluate its ability...
The rise of antibiotic-resistant pathogens, particularly gram-negative bacteria, highlights the urgent need for novel therapeutics. Drug-resistant infections now contribute to approximately 5 million deaths annually, yet traditional antibiotic discov...
Antimicrobial resistance (AMR) represents a critical global health challenge, demanding rapid and accurate antimicrobial susceptibility testing (AST) to guide timely treatments. Traditional culture-based AST methods are slow, while existing whole-gen...
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