BACKGROUND: Prostate cancer (PCa) in the transition zone (TZ) is uncommon and often poses challenges for early diagnosis, but its genomic determinants and therapeutic vulnerabilities remain poorly characterized.
International journal of molecular sciences
Apr 13, 2025
Breast cancer (BRCA) continues to pose a serious risk to women's health worldwide. Neoadjuvant chemotherapy (NAC) is a critical treatment strategy. Nevertheless, the heterogeneity in treatment outcomes necessitates the identification of reliable biom...
International journal of medical sciences
Apr 13, 2025
This study measures expression of () and related cytokine genes in bone marrow mononuclear cells in patients with hematological malignancies, analyzing the relationship between them with an integrated framework of statistical analyses, machine learn...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Apr 12, 2025
A self-developed aberration-free line scanning confocal Raman imager (AFLSCRI) with a spectral resolution of 0.12 nm and a spatial resolution of 2 μm is utilized to diagnose colorectal cancer. The tissues were categorized into four subgroups (typical...
Clinica chimica acta; international journal of clinical chemistry
Apr 12, 2025
Non-invasive diagnostic monitoring techniques have become essential for treating lung cancer (LC), which continues to be the primary cause of cancer-related death worldwide. The new diagnostic biomarkers called tumour-educated platelets (TEPs) show s...
Early screening for cancer has proven to improve the survival rate and spare patients from intensive and costly treatments due to late diagnosis. Cancer screening in the healthy population involves an initial risk stratification step to determine the...
Isocitrate dehydrogenase-mutant gliomas are lethal brain cancers that impair quality of life in young adults. Although less aggressive than glioblastomas, IDH-mutant gliomas invariably progress to incurable disease with unpredictable recurrence. A be...
The expression levels of microRNAs (miRNAs) are strongly linked to cancer progression, making them promising biomarkers for cancer detection. Enzyme-free signal amplification DNA circuits have facilitated the detection of low-abundance miRNAs. Howeve...
Over the past several decades, there has been a significant increase in the number of breast cancer patients. Among the four subtypes of breast cancer, Her2-positive breast cancer is one of the most aggressive breast cancers. In this study, we screen...
Biochimica et biophysica acta. Molecular basis of disease
Apr 9, 2025
Despite advances in cancer diagnosis and treatment, the disease remains a major health challenge. Integrating multi-omics, radiomics, and artificial intelligence has improved detection, prognosis, and treatment monitoring. Molecular multi-omics provi...
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