AIMC Topic: Biosensing Techniques

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Artificial Intelligence-Guided Gut-Microenvironment-Triggered Imaging Sensor Reveals Potential Indicators of Parkinson's Disease.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Apr 3, 2024
The gut-brain axis has recently emerged as a crucial link in the development and progression of Parkinson's disease (PD). Dysregulation of the gut microbiota has been implicated in the pathogenesis of this disease, sparking growing interest in the qu...
Artificial Intelligence Biomarkers Animals Humans Gastrointestinal Microbiome Parkinson Disease Brain-Gut Axis Deep Learning Biosensing Techniques
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Machine Learning-Assistant Colorimetric Sensor Arrays for Intelligent and Rapid Diagnosis of Urinary Tract Infection.

ACS sensors Mar 26, 2024
Urinary tract infections (UTIs), which can lead to pyelonephritis, urosepsis, and even death, are among the most prevalent infectious diseases worldwide, with a notable increase in treatment costs due to the emergence of drug-resistant pathogens. Cur...
Urinary Tract Infections Humans Machine Learning Biosensing Techniques Colorimetry Iron
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Surface-functionalized SERS platform for deep learning-assisted diagnosis of Alzheimer's disease.

Biosensors & bioelectronics Feb 12, 2024
Early diagnosis of Alzheimer's disease is crucial to stall the deterioration of brain function, but conventional diagnostic methods require complicated analytical procedures or inflict acute pain on the patient. Then, label-free Surface-enhanced Rama...
Artificial Intelligence Biomarkers Deep Learning Humans Metal Nanoparticles Biosensing Techniques Amyloid beta-Peptides Spectrum Analysis, Raman Alzheimer Disease
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AIEgen-deep: Deep learning of single AIEgen-imaging pattern for cancer cell discrimination and preclinical diagnosis.

Biosensors & bioelectronics Feb 7, 2024
This study introduces AIEgen-Deep, an innovative classification program combining AIEgen fluorescent dyes, deep learning algorithms, and the Segment Anything Model (SAM) for accurate cancer cell identification. Our approach significantly reduces manu...
Deep Learning Biosensing Techniques Early Detection of Cancer Algorithms Neoplasms Breast Humans
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Mesophilic Argonaute-Mediated Polydisperse Droplet Biosensor for Amplification-Free, One-Pot, and Multiplexed Nucleic Acid Detection Using Deep Learning.

Analytical chemistry Jan 23, 2024
Detection of nucleic acids from a single multiplexed and amplification-free test is critical for ensuring food safety, clinical diagnostics, and environmental monitoring. In this study, we introduced a mesophilic Argonaute protein from (CbAgo), whic...
Nucleic Acids Argonaute Proteins Deep Learning Nucleic Acid Amplification Techniques Biosensing Techniques DNA
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Cellular nucleus image-based smarter microscope system for single cell analysis.

Biosensors & bioelectronics Jan 18, 2024
Cell imaging technology is undoubtedly a powerful tool for studying single-cell heterogeneity due to its non-invasive and visual advantages. It covers microscope hardware, software, and image analysis techniques, which are hindered by low throughput ...
Microscopy, Fluorescence Single-Cell Analysis Image Processing, Computer-Assisted Artificial Intelligence Biosensing Techniques Software
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DNA Robots for CRISPR/Cas12a Activity Management and Universal Platforms for Biosensing.

Analytical chemistry Jan 13, 2024
The CRISPR/Cas12a system is a revolutionary genome editing technique that is widely employed in biosensing and molecular diagnostics. However, there are few reports on precisely managing the -cleavage activity of Cas12a by simple modification since t...
Robotics DNA Colorimetry Excision Repair Biosensing Techniques CRISPR-Cas Systems
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Fast Determination of Rutin on a Biosensor Made Using a Layered Double Hydroxide Nanocomposite Modified Electrode.

Biosensors Dec 29, 2023
In this study, a nanocomposite of LDH/graphene/polyaniline/gold (LDH/rGO/PANI/Au) was synthesized and characterized. The results of characterization showed that the composite material preserved the layered structure of LDH. The composite was dropped ...
Nanocomposites Laccase Biosensing Techniques Electrodes Rutin
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Faradaic Impedimetric Immunosensor for Label-Free Point-of-Care Detection of COVID-19 Antibodies Using Gold-Interdigitated Electrode Array.

Biosensors Dec 22, 2023
Label-free electrochemical biosensors have many desirable characteristics in terms of miniaturization, scalability, digitization, and other attributes associated with point-of-care (POC) applications. In the era of COVID-19 and pandemic preparedness,...
Antibodies, Monoclonal, Humanized Gold Immunoassay Humans Biosensing Techniques Electrodes Spike Glycoprotein, Coronavirus SARS-CoV-2 Point-of-Care Systems COVID-19
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De novo design of high-affinity binders of bioactive helical peptides.

Nature Dec 18, 2023
Many peptide hormones form an α-helix on binding their receptors, and sensitive methods for their detection could contribute to better clinical management of disease. De novo protein design can now generate binders with high affinity and specificity ...
Diffusion Parathyroid Hormone Protein Structure, Secondary Glucagon Substrate Specificity Models, Molecular Luminescent Measurements Computer-Aided Design Mass Spectrometry Deep Learning Peptides Proteins Biosensing Techniques
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