Cytometry. Part A : the journal of the International Society for Analytical Cytology
38357742
Imaging flow cytometry is an attractive method to investigate individual cells by optical properties. However, imaging flow cytometry applications with clinical relevance are scarce so far. Platelet aggregation naturally occurs during blood coagulati...
International journal of molecular sciences
38892129
This study focuses on understanding the transcriptional heterogeneity of activated platelets and its impact on diseases such as sepsis, COVID-19, and systemic lupus erythematosus (SLE). Recognizing the limited knowledge in this area, our research aim...
The last decade has seen increasing use of advanced imaging techniques in platelet research. However, there has been a lag in the development of image analysis methods, leaving much of the information trapped in images. Herein, we present a robust an...
Liquid biopsy demonstrates excellent potential in patient management by providing a minimally invasive and cost-effective approach to detecting and monitoring cancer, even at its early stages. Due to the complexity of liquid biopsy data, machine-lear...
International journal of laboratory hematology
39032139
INTRODUCTION: This study aims to assess the performance of the platelet count estimation using artificial intelligence technology on the MC-80 digital morphology analyzer.
Fluorescence intravital microscopy captures large data sets of dynamic multicellular interactions within various organs such as the lungs, liver, and brain of living subjects. In medical imaging, edge detection is used to accurately identify and deli...
Journal of chemical information and modeling
39109515
Thrombocytopenia, which is associated with thrombopoietin (TPO) deficiency, presents very limited treatment options and can lead to life-threatening complications. Discovering new therapeutic agents against thrombocytopenia has proven to be a challen...
International journal of laboratory hematology
39099371
INTRODUCTION: The platelet fluorescent counting (PLT-F) method is utilized as a reflex test method following the initial test of the platelet impedance counting (PLT-I) method in clinical practice on the Sysmex XN-series automated hematology analyzer...
Journal of the Optical Society of America. A, Optics, image science, and vision
39889090
We developed a new method to enhance the resolution of blood platelet aggregates imaged via quantitative phase imaging (QPI) using a Pix2Pix generative adversarial network (GAN). First, 1 µm polystyrene beads were imaged with low- and high-resolution...
Asian Pacific journal of cancer prevention : APJCP
39733436
INTRODUCTION: Colorectal cancer (CRC) staging is essential for effective treatment planning and prognosis. While platelet indices have shown promise in indicating CRC aggressiveness, a platelet index-based predictor for CRC staging has not been estab...