Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a gradual decline in cognitive ability and memory function. It is a progressive disease characterized by worsening dementia symptoms over time, starting with mild m...
Neurons in the brain are known to encode diverse information through their spiking activity, primarily reflecting external stimuli and internal states. However, whether individual neurons also embed information about their own anatomical location wit...
Speech Imagery (SI) refers to the mental experience of hearing speech and may be the core of verbal thinking for people who undergo internal monologues. It belongs to the set of possible mental imagery states that produce kinesthetic experiences whos...
BACKGROUND: Rhegmatogenous retinal detachment (RRD) is known to induce functional alterations in the gray matter regions associated with vision. However, the impact of RRD on the white matter (WM) connectome remains largely unexplored.
Functional brain network (FBN) derived from functional Magnetic Resonance Imaging (fMRI) has promising prospects in clinical research, but fMRI is not a routine acquisition data, which limits its popularity in clinical applications. Therefore, it is ...
Acquiring high-resolution (HR) MR images of infant brains is challenging due to lengthy scan times and limited subject compliance. Image super-resolution (SR) techniques can generate HR images from low-resolution (LR) inputs, reducing the need for ex...
BACKGROUND: Automated whole-brain delineation (WBD) techniques often struggle to generalize across pre-clinical studies due to variations in animal models, magnetic resonance imaging (MRI) scanners, and tissue contrasts. We developed a 3D U-Net neura...
Tractography uses diffusion Magnetic Resonance Imaging (dMRI) to noninvasively reconstruct brain white matter (WM) tracts, with Convolutional Neural Network (CNNs) like U-Net significantly advancing accuracy in medical image segmentation. This work p...
Galectin-3 (Gal-3) has emerged as a critical regulator of neuroinflammation and a promising therapeutic target for Alzheimer's disease (AD). Nevertheless, the development of brain-penetrant small-molecule Gal-3 inhibitors poses a significant challeng...
The debate on whether feature attention (FA) and spatial attention (SA) share a common neural mechanism remains unresolved. Previous neuroimaging studies have identified fronto-parietal-temporal attention-related regions that exhibited consistent act...
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