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Robotic distal locking of intramedullary nailing: Technical description and cadaveric testing.

The international journal of medical robotics + computer assisted surgery : MRCAS
Interlocked intramedullary nailing is the treatment of choice for femoral shaft fractures. However, distal locking is a technically challenging part of the procedure that can result in distal femoral malrotation and high radiation exposure. We have t...

RABiT-II: Implementation of a High-Throughput Micronucleus Biodosimetry Assay on Commercial Biotech Robotic Systems.

Radiation research
We demonstrate the use of high-throughput biodosimetry platforms based on commercial high-throughput/high-content screening robotic systems. The cytokinesis-block micronucleus (CBMN) assay, using only 20 μl whole blood from a fingerstick, was impleme...

Estimation of adsorption isotherm and mass transfer parameters in protein chromatography using artificial neural networks.

Journal of chromatography. A
Mechanistic modeling has been repeatedly successfully applied in process development and control of protein chromatography. For each combination of adsorbate and adsorbent, the mechanistic models have to be calibrated. Some of the model parameters, s...

Geographical traceability of wild Boletus edulis based on data fusion of FT-MIR and ICP-AES coupled with data mining methods (SVM).

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
In this work, the data fusion strategy of Fourier transform mid infrared (FT-MIR) spectroscopy and inductively coupled plasma-atomic emission spectrometry (ICP-AES) was used in combination with Support Vector Machine (SVM) to determine the geographic...

Quantification of the 3α and 3β epimers of 25-hydroxyvitamin D in dried blood spots by LC-MS/MS using artificial whole blood calibration and chemical derivatization.

Talanta
While the biological function of the 3α epimer of 25-hydroxyvitamin D (25(OH)D) remains unknown, its presence needs to be accurately captured and separated from the main 3β epimer, to avoid positive bias in vitamin D status analyses. Several recent L...

An LC-MS/MS method for the determination of digitoxigenin in skin samples and its application to skin permeation and metabolic stability studies.

Journal of pharmaceutical and biomedical analysis
An LC-MS/MS method was developed for the determination of digitoxigenin in mice skin samples. Chromatographic separation was achieved on an Agilent Poroshell 120 EC-C18 column. Mass spectrometric detection was achieved by a triple-quadrupole mass spe...

MIL-101(Cr) as matrix for sensitive detection of quercetin by matrix-assisted laser desorption/ionization mass spectrometry.

Talanta
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) has been proven as a useful and advanced technique in the identification of polymers and proteins. However, MALDI-TOF-MS still has the unavoidable drawback of...

Air assisted emulsification liquid-liquid microextraction based on deep eutectic solvent for preconcentration of methadone in water and biological samples.

Talanta
Nowadays, a deep eutectic solvent (DES) has recently been considered as a green ion liquid analogue. In this study, a new compound of DES has been synthesized as an extraction solvent in air assistedemulsification liquid-liquid microextraction method...

Minimalistic optic flow sensors applied to indoor and outdoor visual guidance and odometry on a car-like robot.

Bioinspiration & biomimetics
Here we present a novel bio-inspired optic flow (OF) sensor and its application to visual  guidance and odometry on a low-cost car-like robot called BioCarBot. The minimalistic OF sensor was robust to high-dynamic-range lighting conditions and to var...

Aerodynamic parameters from distributed heterogeneous CNT hair sensors with a feedforward neural network.

Bioinspiration & biomimetics
Distributed arrays of artificial hair sensors have bio-like sensing capabilities to obtain spatial and temporal surface flow information which is an important aspect of an effective fly-by-feel system. The spatiotemporal surface flow measurement enab...