AIMC Topic: Capsules

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Magnetically Actuated Heterogeneous Microcapsule-Robot for the Construction of 3D Bioartificial Architectures.

ACS applied materials & interfaces
Core-shell microcapsules as one type of the most attractive carriers and reactors have been widely applied in the fields of drug screening and tissue engineering owing to their excellent biocompatibility and semi-permeability. Yet, the spatial organi...

A Capsule-Type Microrobot with Pick-and-Drop Motion for Targeted Drug and Cell Delivery.

Advanced healthcare materials
A capsule-type microrobot exhibits "pick-and-drop" (P&D) motion to hold a particle within a confined volume and transports it via a corkscrewing motion. The P&D motion is possible because the capsule-type microrobot has two parts: a plunger and a cap...

A novel method for the production of core-shell microparticles by inverse gelation optimized with artificial intelligent tools.

International journal of pharmaceutics
Numerous studies have been focused on hydrophobic compounds encapsulation as oils. In fact, oils can provide numerous health benefits as synergic ingredient combined with other hydrophobic active ingredients. However, stable microparticles for pharma...

Highly sensitive colorimetric aptasensor for ochratoxin A detection based on enzyme-encapsulated liposome.

Analytica chimica acta
A simple, low-cost, and sensitive liposome-based colorimetric aptasensor has been developed to detect ochratoxin A (OTA). Specifically, a dumbbell-shaped probe was designed, including magnetic beads (MBs), double-stranded DNA (dsDNA), and enzyme-enca...

A validated capillary electrophoretic method for the determination of indacaterol and its application to a pharmaceutical preparation.

Journal of food and drug analysis
Indacaterol is a new inhaled ultra-long acting β-agonist. It has been recently approved in the European Union for the treatment of chronic obstructive pulmonary disease. This paper reports, for the first time, a method for the determination and valid...

Scaling effects in spiral capsule robots.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Spiral capsule robots can be applied to human gastrointestinal tracts and blood vessels. Because of significant variations in the sizes of the inner diameters of the intestines as well as blood vessels, this research has been unable to meet the requi...

RSM and ANN modeling-based optimization approach for the development of ultrasound-assisted liposome encapsulation of piceid.

Ultrasonics sonochemistry
Piceid, a naturally occurring derivative of resveratrol found in many plants, has recently been considered as a potential nutraceutical. However, its poorly water-soluble property could cause a coupled problem of biological activities concerning drug...

A Strategy based on Bioinformatics and Machine Learning Algorithms Reveals Potential Mechanisms of Shelian Capsule against Hepatocellular Carcinoma.

Current pharmaceutical design
BACKGROUND: Hepatocellular carcinoma (HCC) is a prevalent and life-threatening form of cancer, with Shelian Capsule (SLC), a traditional Chinese medicine (TCM) formulation, being recommended for clinical treatment. However, the mechanisms underlying ...

A neural network-based algorithm for high-throughput characterisation of viscoelastic properties of flowing microcapsules.

Soft matter
Microcapsules, consisting of a liquid droplet enclosed by a viscoelastic membrane, have a wide range of biomedical and pharmaceutical applications and also serve as a popular mechanical model for biological cells. In this study, we develop a novel hi...

A novel fast solving method for targeted drug-delivery capsules in the gastrointestinal tract.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: As an innovative technique without cable connection, targeted drug-delivery capsules improve diagnostic and therapeutic capabilities in the gastrointestinal (GI) tract.