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Multivariate classification of drug-naive obsessive-compulsive disorder patients and healthy controls by applying an SVM to resting-state functional MRI data.

BMC psychiatry
BACKGROUND: Previous resting-state functional magnetic resonance imaging (rs-fMRI) studies have revealed intrinsic regional activity alterations in obsessive-compulsive disorder (OCD), but those results were based on group analyses, which limits thei...

Using Recurrent Neural Networks to Compare Movement Patterns in ADHD and Normally Developing Children Based on Acceleration Signals from the Wrist and Ankle.

Sensors (Basel, Switzerland)
Attention deficit and hyperactivity disorder (ADHD) is a neurodevelopmental condition that affects, among other things, the movement patterns of children suffering it. Inattention, hyperactivity and impulsive behaviors, major symptoms characterizing ...

Identification of a Multiplex Biomarker Panel for Hypertrophic Cardiomyopathy Using Quantitative Proteomics and Machine Learning.

Molecular & cellular proteomics : MCP
Hypertrophic cardiomyopathy (HCM) is defined by pathological left ventricular hypertrophy (LVH). It is the commonest inherited cardiac condition and a significant number of high risk cases still go undetected until a sudden cardiac death (SCD) event....

3D-CNN based discrimination of schizophrenia using resting-state fMRI.

Artificial intelligence in medicine
MOTIVATION: This study reports a framework to discriminate patients with schizophrenia and normal healthy control subjects, based on magnetic resonance imaging (MRI) of the brain. Resting-state functional MRI data from a total of 144 subjects (72 pat...

Automatic Segmentation, Detection, and Diagnosis of Abdominal Aortic Aneurysm (AAA) Using Convolutional Neural Networks and Hough Circles Algorithm.

Cardiovascular engineering and technology
PURPOSE: An abdominal aortic aneurysm (AAA) is known as a cardiovascular disease involving localized deformation (swelling or enlargement) of aorta occurring between the renal and iliac arteries. AAA would jeopardize patients' lives due to its ruptur...

Diagnosis of Alzheimer's disease with Sobolev gradient-based optimization and 3D convolutional neural network.

International journal for numerical methods in biomedical engineering
Alzheimer's disease is a neuropsychiatric, progressive, also an irreversible disease. There is not an effective cure for the disease. However, early diagnosis has an important role for treatment planning to delay its progression since the treatments ...

Diagnostic value of spirometry vs impulse oscillometry: A comparative study in children with sickle cell disease.

Pediatric pulmonology
BACKGROUND: Spirometry is conventionally used to diagnose airway diseases in children with sickle cell disease (C-SCD). However, spirometry is difficult for younger children to perform, is effort dependent, and it provides limited information on resp...

Modelling disease risk for amyloid A (AA) amyloidosis in non-human primates using machine learning.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
Amyloid A (AA) amyloidosis is found in humans and non-human primates, but quantifying disease risk prior to clinical symptoms is challenging. We applied machine learning to identify the best predictors of amyloidosis in rhesus macaques from availabl...

An intelligent warning model for early prediction of cardiac arrest in sepsis patients.

Computer methods and programs in biomedicine
BACKGROUND: Sepsis-associated cardiac arrest is a common issue with the low survival rate. Early prediction of cardiac arrest can provide the time required for intervening and preventing its onset in order to reduce mortality. Several studies have be...

Machine-learning based brain age estimation in major depression showing no evidence of accelerated aging.

Psychiatry research. Neuroimaging
Molecular biological findings indicate that affective disorders are associated with processes akin to accelerated aging of the brain. The use of the BrainAGE (brain age estimation gap) framework allows machine-learning based detection of a gap betwee...