OBJECTIVE: The presence of pancreaticobiliary maljunction (PBM) in pediatric patients with congenital choledochal malformation significantly impacts clinical management and surgical decision-making. Current preoperative evaluation of PBM coexistence ...
The gold standard for the diagnosis of sleep apnoea (SA) is polysomnography, consisting of overnight in-lab tests, which are expensive for both patients and healthcare systems. Airflow and pulse/oximetry signals contain most of the necessary informat...
BACKGROUND: Hookworm infection, a neglected tropical disease (NTD) causing iron-deficiency anaemia and malnutrition in low-income populations with poor sanitation, poses a considerable public health challenge in China and worldwide.
Physical literacy in children has become a significant research topic in both education and psychology. Recently, machine learning, as a cutting-edge AI technology, has started to play a crucial role in these fields. This study aimed to apply machine...
BACKGROUND: Pediatric cholestatic liver diseases can be characterized by rapidly progressive fibrosis. A multicenter cross-sectional analysis of vibration-controlled elastography in biliary atresia (BA), alpha-1 antitrypsin deficiency (A1AT), and Ala...
DNA methylation-based classification using the Heidelberg Classifier is a state-of-the-art data-driven method for molecular diagnosis of central nervous system (CNS) tumors. However, many pediatric low-grade glioma (pLGG) samples fail to yield a conf...
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Sep 27, 2025
PURPOSE: Tumors are heterogeneous and consist of subregions, also known as tumor habitats, each of which corresponds to a group of tissues with similar structural, metabolic or functional characteristics. This study aims to visualize and quantify int...
Since the COVID-19 pandemic, there has been a notable resurgence of pneumonia (MPP) in children, with a concerning rise in the severity of cases. Although changes in post-pandemic respiratory infection patterns have been documented, the reasons behi...
Molecular medicine (Cambridge, Mass.)
Sep 25, 2025
BACKGROUND: Juvenile idiopathic arthritis (JIA) is a rare autoimmune disease arising from a complex interplay between genetic and environmental factors. Epigenetic modifications such as DNA methylation (DNAm) have been described as potential mediator...
Assessing skeletal maturity through bone age (BA) evaluation is crucial for monitoring children's growth and guiding treatments, such as hormonal therapy and orthopedic interventions. In recent years, artificial intelligence (AI) methods have been de...
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