AIMC Topic: Child, Preschool

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Identifying determinants of under-5 mortality in Bangladesh: A machine learning approach with BDHS 2022 data.

PloS one
BACKGROUND: Under-5 mortality in Bangladesh remains a critical indicator of public health and socio-economic development. Traditional methods often struggle to capture the complex, non-linear relationships influencing under-5 mortality. This study le...

Interpretable web-based machine learning model for predicting intravenous immunoglobulin resistance in Kawasaki disease.

Italian journal of pediatrics
BACKGROUND: Kawasaki disease (KD) is a leading cause of acquired heart disease in children that is treated with intravenous immunoglobulin (IVIG). However, 10-20% of cases exhibit IVIG resistance, which increases the risk of coronary complications. E...

Interpretable machine learning models for predicting childhood myopia from school-based screening data.

Scientific reports
This study assessed the efficacy of various diagnostic indicators and machine learning (ML) models in predicting childhood myopia. A total of 2,365 children aged 5-12 years were included in the study. The participants were exposed to non-cycloplegic ...

An interpretable deep learning approach for autism spectrum disorder detection in children using NASNet-mobile.

Biomedical physics & engineering express
Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder featuring impaired social interactions and communication abilities engaging the individuals in a restrictive or repetitive behaviour. Though incurable early detection and in...

Integrative machine learning identifies robust inflammation-related diagnostic biomarkers and stratifies immune-heterogeneous subtypes in Kawasaki disease.

Pediatric rheumatology online journal
BACKGROUND: Kawasaki disease (KD), a pediatric systemic vasculitis, lacks reliable diagnostic biomarkers and exhibits immune heterogeneity, complicating clinical management. Current therapies face challenges in targeting specific immune pathways and ...

Comparison of salivary statherin and beta-defensin-2 levels, oral health behaviors, and demographic factors in children with and without early childhood caries.

BMC oral health
BACKGROUND: Early childhood caries (ECC) is a widespread pediatric dental condition that is influenced by a combination of biological, behavioral, and demographic factors. Salivary biomarkers, including beta-defensin-2 (BD-2) and statherin (STATH), o...

Single-tooth resolved, whole-mouth prediction of early childhood caries via spatiotemporal variations of plaque microbiota.

Cell host & microbe
Early childhood caries (ECC) exhibits tooth specificity, highlighting the need for single-tooth-level prevention. We profiled 2,504 dental plaque microbiota samples from 89 preschoolers across two cohorts, tracking compositional changes with imputed ...

Undesired nexus poor health status of child under-five: A case study of Pakistan.

PloS one
Childhood morbidity and mortality are key indicators of human development, particularly reflecting poor health conditions in children. In Pakistan, child mortality remains a serious problem despite efforts to reduce it. One factor that may be associa...

Associations of greenhouse gases, air pollutants and dynamics of scrub typhus incidence in China: a nationwide time-series study.

BMC public health
BACKGROUND: Environmental factors have been identified as significant risk factors for scrub typhus. However, the impact of inorganic compounds such as greenhouse gases and air pollutants on the incidence of scrub typhus has not been evaluated.

Development of a machine learning-based predictive nomogram for screening children with juvenile idiopathic arthritis: a pseudo-longitudinal study of 223,195 children in the United States.

Frontiers in public health
BACKGROUND: Juvenile idiopathic arthritis (JIA) is a prevalent chronic rheumatological condition in children, with reported prevalence ranging from 12. 8 to 45 per 100,000 and incidence rates from 7.8 to 8.3 per 100,000 person-years. The diagnosis of...