Molecular medicine (Cambridge, Mass.)
Sep 25, 2025
BACKGROUND: Juvenile idiopathic arthritis (JIA) is a rare autoimmune disease arising from a complex interplay between genetic and environmental factors. Epigenetic modifications such as DNA methylation (DNAm) have been described as potential mediator...
BACKGROUND AND OBJECTIVES: Wilson disease (WD), an inherited copper metabolism disorder, is a cause of acute-on-chronic liver failure (ACLF), posing life-threatening risks due to rapid progression. This study aimed to develop a machine learning (ML)-...
BACKGROUND: This study aimed to evaluate the accuracy and completeness of Chat Generative Pre-trained Transformer-4 (ChatGPT-4) responses to frequently asked questions (FAQs) posed by patients and parents, as well as curricular questions related to p...
Assessing skeletal maturity through bone age (BA) evaluation is crucial for monitoring children's growth and guiding treatments, such as hormonal therapy and orthopedic interventions. In recent years, artificial intelligence (AI) methods have been de...
OBJECTIVE: This study evaluates the performance of four large language models-ChatGPT 4o, ChatGPT o1-mini, Gemini 2.0 Flash, and Gemini 1.5 Flash-in answering multiple-choice questions in child and adolescent psychiatry to assess their level of factu...
Development of dental caries is a dynamic process; yet, there is limited knowledge on microbial differences at various stages of caries at higher resolution. To investigate the shifting microbiome profiles across different caries stages, 30 children ...
BACKGROUND: Circumcision is a widely practiced procedure with cultural and medical significance. However, certain penile abnormalities-such as hypospadias or webbed penis-may contraindicate the procedure and require specialized care. In low-resource ...
According to productive failure (PF) theory, experiencing failure during problem-solving can enhance students' knowledge acquisition in subsequent instruction. However, challenging students with problems beyond their current capabilities may strain t...
Reading fluency is a vital building block for developing literacy, yet the best way to practice fluency-reading aloud-can cause anxiety severe enough to inhibit literacy development in ways that can have an adverse effect on students through adulthoo...
Student dropout is a significant challenge in Bangladesh, with serious impacts on both educational and socio-economic outcomes. This study investigates the factors influencing school dropout among students aged 6-24 years, employing data from the 201...
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