BACKGROUND: Type 2 diabetes (T2D) and its vascular complications, including diabetic retinopathy (DR), are escalating in prevalence globally, with disproportionately high prevalence in Middle Eastern populations, where genetic predispositions and lif...
BACKGROUND: The clinical significance and contribution of the lipid profile in atherosclerosis are well established. However, further investigation is needed in stroke patients, particularly regarding apolipoprotein B100 (ApoB100), a novel non-tradit...
Research aimed at understanding how baseline clinical and demographic characteristics influence outcomes over time is critically important to inform individualized therapeutic programs for children with neurodevelopmental differences. This study char...
BACKGROUND: Drug-drug interactions (DDIs) are a major concern, especially for older adults taking multiple medications. Although Health Canada and the US Food and Drug Administration (FDA) use population-based studies to identify adverse drug events,...
BACKGROUND: Lysosomal storage diseases (LSDs) are a group of genetically heterogeneous inherited metabolic disorders that affect the functions of the lysosomes in different human tissues. Mucopolysaccharidosis IIIB (MPS IIIB), Sanfilippo B syndrome, ...
The gut microbiota is profoundly influenced by dietary choices, with emerging evidence linking it to various health outcomes. Here, we investigate diet-microbiota associations using detailed temporal nutrition intake data captured through real-time f...
AIM: To identify subgroups of early rheumatoid arthritis (RA) based on comorbidities and RA manifestations and to investigate their associated risks of cardiovascular events and mortality.
PURPOSE: Postoperative fever is a common complication following percutaneous nephrolithotomy (PCNL) that occurs even in patients with sterile urine cultures. Traditional risk-assessment tools are insufficient in this subset of patients. This study ai...
BACKGROUND: A significant number of individuals undergoing coronary computed tomography angiography (CCTA) for suspected (CAD) have nonobstructive or no CAD. There is a need for clinically proven models that can predict the pretest probability of sta...
Imaging technologies and staining based pathology are important components of common practice cancer care. Specifically, H&E imaging is standard for almost all cancer patients. Traditionally, H&E images can serve, when used by experienced trained pat...
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