AIMC Topic: Cohort Studies
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Machine learning for the prediction of spontaneous preterm birth using early second and third trimester maternal blood gene expression: A cautionary tale.
PloS one
Jun 27, 2025
Spontaneous preterm birth (sPTB) remains a significant global health challenge and a leading cause of neonatal mortality and morbidity. Despite advancements in neonatal care, the prediction of sPTB remains elusive, in part due to complex etiologies a...
Development of Machine Learning-Based Risk Prediction Models to Predict Rapid Weight Gain in Infants: Analysis of Seven Cohorts.
JMIR public health and surveillance
Jun 18, 2025
BACKGROUND: Rapid weight gain (RWG) during infancy, defined as an upward crossing of one centile line on a weight growth chart, is highly predictive of subsequent obesity risk. Identification of infant RWG could facilitate obesity risk assessment fro...
Exploratory multi-cohort, multi-reader study on the clinical utility of a deep learning model for transforming cryosectioned to formalin-fixed, paraffin-embedded (FFPE) images in breast lesion diagnosis.
Breast cancer research : BCR
Jun 17, 2025
BACKGROUND: Cryosectioned tissues often exhibit artifacts that compromise pathologists' diagnostic accuracy during intraoperative assessments. These inconsistencies, compounded by variations in frozen section (FS) production across laboratories, high...
Fecal gut microbiota and amino acids as noninvasive diagnostic biomarkers of Pediatric inflammatory bowel disease.
Gut microbes
Jun 12, 2025
BACKGROUND AND AIMS: Fecal calprotectin (FCP) has limited specificity as diagnostic biomarker of pediatric inflammatory bowel disease (IBD), leading to unnecessary invasive endoscopies. This study aimed to develop and validate a fecal microbiota and ...
Patterns of calcitonin gene-related peptide monoclonal antibody use in people with migraine: Results of the OVERCOME (US) study.
Cephalalgia : an international journal of headache
Jun 12, 2025
BackgroundUnderstanding characteristics and reasons associated with using calcitonin gene-related peptide monoclonal antibodies (CGRP mAb) for migraine prevention may help clinicians individualize treatment plans and achieve better patient outcomes.M...
Air Pollution and Autism Spectrum Disorder: Unveiling Multipollutant Risks and Sociodemographic Influences in California.
Environmental health perspectives
Jun 12, 2025
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental condition with increasing prevalence worldwide. Air pollution may be a major contributor to the rise in ASD cases. This study investigated how the risk of ASD associated with prenatal...
Identifying patients at risk of increased health utilization following lumbar spine surgery.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Jun 11, 2025
BACKGROUND: Adequate preoperative identification of patients at risk of significant healthcare utilization after surgery could help guide preoperative decision-making as well as postoperative patient management. While several studies have proposed me...
Comparison of Multimodal Deep Learning Approaches for Predicting Clinical Deterioration in Ward Patients: Observational Cohort Study.
Journal of medical Internet research
Jun 11, 2025
BACKGROUND: Implementing machine learning models to identify clinical deterioration in the wards is associated with decreased morbidity and mortality. However, these models have high false positive rates and only use structured data.
Explainable machine learning model for predicting internal mammary node metastasis in breast cancer: Multi-method development and cross-cohort validation.
Breast (Edinburgh, Scotland)
Jun 9, 2025
BACKGROUND: This study developed an explainable machine learning model for baseline internal mammary lymph node metastasis (IMNM) in breast cancer patients.
Diagnostic performances of hysteroscopy in post-remission surveillance of patients treated conservatively for endometrial cancer and atypical hyperplasia: a cohort study.
European journal of obstetrics, gynecology, and reproductive biology
Jun 4, 2025
OBJECTIVE: Hysteroscopy is commonly used for diagnosing benign endometrial conditions, but its diagnostic performance in malignancies post-treatment surveillance has not been evaluated. This study evaluated the correlation between hysteroscopic appea...
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