AIMC Topic: Colorectal Neoplasms

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A machine-learning approach for predicting palmitoylation sites from integrated sequence-based features.

Journal of bioinformatics and computational biology
Palmitoylation is the covalent attachment of lipids to amino acid residues in proteins. As an important form of protein posttranslational modification, it increases the hydrophobicity of proteins, which contributes to the protein transportation, orga...

Models of logistic regression analysis, support vector machine, and back-propagation neural network based on serum tumor markers in colorectal cancer diagnosis.

Genetics and molecular research : GMR
We evaluated the application of three machine learning algorithms, including logistic regression, support vector machine and back-propagation neural network, for diagnosing congenital heart disease and colorectal cancer. By inspecting related serum t...

Metastatic liver tumour segmentation with a neural network-guided 3D deformable model.

Medical & biological engineering & computing
The segmentation of liver tumours in CT images is useful for the diagnosis and treatment of liver cancer. Furthermore, an accurate assessment of tumour volume aids in the diagnosis and evaluation of treatment response. Currently, segmentation is perf...

Utilizing uncoded consultation notes from electronic medical records for predictive modeling of colorectal cancer.

Artificial intelligence in medicine
OBJECTIVE: Machine learning techniques can be used to extract predictive models for diseases from electronic medical records (EMRs). However, the nature of EMRs makes it difficult to apply off-the-shelf machine learning techniques while still exploit...

Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity.

BMC systems biology
BACKGROUND: High throughput technologies have been used to profile genes in multiple different dimensions, such as genetic variation, copy number, gene and protein expression, epigenetics, metabolomics. Computational analyses often treat these differ...

Comparison of bleeding risks related to venous thromboembolism prophylaxis in laparoscopic vs open colorectal cancer surgery: a multicenter study in Japanese patients.

American journal of surgery
BACKGROUND: Venous thromboembolism is the most common preventable cause of hospital death. The objective of this study was to clarify risk factors for postoperative bleeding related to thromboprophylaxis after laparoscopic colorectal cancer surgery.

The relationship of blood transfusion with peri-operative and long-term outcomes after major hepatectomy for metastatic colorectal cancer: a multi-institutional study of 456 patients.

HPB : the official journal of the International Hepato Pancreato Biliary Association
BACKGROUND: Data on prognostic implications of peri-operative blood transfusion around resection of colorectal cancer liver metastases (CRLM) are conflicting. This retrospective study assesses the association of transfusion with complications and dis...

Current state of micro-robots/devices as substitutes for screening colonoscopy: assessment based on technology readiness levels.

Surgical endoscopy
BACKGROUND: Previous reports have described several candidates, which have the potential to replace colonoscopy, but to date, there is still no device capable of fully replacing flexible colonoscopy in the management of colonic disorders and for mass...

The use of artificial neural networks to predict delayed discharge and readmission in enhanced recovery following laparoscopic colorectal cancer surgery.

Techniques in coloproctology
BACKGROUND: Artificial neural networks (ANNs) can be used to develop predictive tools to enable the clinical decision-making process. This study aimed to investigate the use of an ANN in predicting the outcomes from enhanced recovery after colorectal...

Multi-center colonoscopy quality measurement utilizing natural language processing.

The American journal of gastroenterology
BACKGROUND: An accurate system for tracking of colonoscopy quality and surveillance intervals could improve the effectiveness and cost-effectiveness of colorectal cancer (CRC) screening and surveillance. The purpose of this study was to create and te...