This study presents the work in predicting crash risk on expressways with consideration of both the impact of safety critical events and traffic conditions. The traffic resilience theory is introduced to learn safety problems from the standpoint of 1...
When incorporating more realistic synaptic dynamics, the computational efficiency of population density methods (PDMs) declines sharply due to the increase in the dimension of master equations. To avoid such a decline, we develop an efficient PDM, te...
This letter deals with neural networks as dynamical systems governed by finite difference equations. It shows that the introduction of -many skip connections into network architectures, such as residual networks and additive dense networks, defines ...
Metabolic models can estimate intrinsic product yields for microbial factories, but such frameworks struggle to predict cell performance (including product titer or rate) under suboptimal metabolism and complex bioprocess conditions. On the other han...
The brain has the ability to flexibly perform many tasks, but the underlying mechanism cannot be elucidated in traditional experimental and modeling studies designed for one task at a time. Here, we trained single network models to perform 20 cogniti...
We consider the ancestral state reconstruction problem where we need to infer phenotypes of ancestors using observations from present-day species. For this problem, we propose a multi-task learning method that uses regularized maximum likelihood to e...
PURPOSE: Robotic stabilization of a therapeutic radiation beam with respect to a dynamically moving tumor target can be accomplished either by moving the radiation source, the patient, or both. As the treatment beam is on during this process, the pri...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
In silico toxicity prediction plays an important role in the regulatory decision making and selection of leads in drug design as in vitro/vivo methods are often limited by ethics, time, budget, and other resources. Many computational methods have bee...
Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
Jan 10, 2019
We introduce here ML4Tox, a framework offering Deep Learning and Support Vector Machine models to predict agonist, antagonist, and binding activities of chemical compounds, in this case for the estrogen receptor ligand-binding domain. The ML4Tox mode...
BACKGROUND: A direct blow to the knee is one way to injure the anterior cruciate ligament (ACL), e.g., during a football or traffic accident. Robot-assisted therapy (RAT) rehabilitation, simulating regular walking, improves walking and balance abilit...
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