AIMC Topic: Deep Learning

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Keratoconus detection using deep learning of colour-coded maps with anterior segment optical coherence tomography: a diagnostic accuracy study.

BMJ open
OBJECTIVE: To evaluate the diagnostic accuracy of keratoconus using deep learning of the colour-coded maps measured with the swept-source anterior segment optical coherence tomography (AS-OCT).

Interpretation of Compound Activity Predictions from Complex Machine Learning Models Using Local Approximations and Shapley Values.

Journal of medicinal chemistry
In qualitative or quantitative studies of structure-activity relationships (SARs), machine learning (ML) models are trained to recognize structural patterns that differentiate between active and inactive compounds. Understanding model decisions is ch...

Deep learning-enabled system for rapid pneumothorax screening on chest CT.

European journal of radiology
PURPOSE: Prompt diagnosis and quantitation of pneumothorax impact decisions pertaining to patient management. The purpose of our study was to develop and evaluate the accuracy of a deep learning (DL)-based image classification program for detection o...

Deep learning for World Health Organization grades of pancreatic neuroendocrine tumors on contrast-enhanced magnetic resonance images: a preliminary study.

International journal of computer assisted radiology and surgery
PURPOSE: The World Health Organization (WHO) grading system of pancreatic neuroendocrine tumor (PNET) plays an important role in the clinical decision. The rarity of PNET often negatively affects the radiological application of deep learning algorith...

Practical High-Quality Electrostatic Potential Surfaces for Drug Discovery Using a Graph-Convolutional Deep Neural Network.

Journal of medicinal chemistry
Inspecting protein and ligand electrostatic potential (ESP) surfaces in order to optimize electrostatic complementarity is a key activity in drug design. These ESP surfaces need to reflect the true electrostatic nature of the molecules, which typical...

Deep Learning in Personalization of Cardiovascular Stents.

Journal of cardiovascular pharmacology and therapeutics
Deep learning (DL) application has demonstrated its enormous potential in accomplishing biomedical tasks, such as vessel segmentation, brain visualization, and speech recognition. This review article has mainly covered recent advances in the principl...

A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis.

The Lancet. Digital health
BACKGROUND: Deep learning offers considerable promise for medical diagnostics. We aimed to evaluate the diagnostic accuracy of deep learning algorithms versus health-care professionals in classifying diseases using medical imaging.

A comparison of machine learning algorithms for the surveillance of autism spectrum disorder.

PloS one
OBJECTIVE: The Centers for Disease Control and Prevention (CDC) coordinates a labor-intensive process to measure the prevalence of autism spectrum disorder (ASD) among children in the United States. Random forests methods have shown promise in speedi...

Super-resolution reconstruction of knee magnetic resonance imaging based on deep learning.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: With the rapid development of medical imaging and intelligent diagnosis, artificial intelligence methods have become a research hotspot of radiography processing technology in recent years. The low definition of knee magneti...

Deep Learning and Glaucoma Specialists: The Relative Importance of Optic Disc Features to Predict Glaucoma Referral in Fundus Photographs.

Ophthalmology
PURPOSE: To develop and validate a deep learning (DL) algorithm that predicts referable glaucomatous optic neuropathy (GON) and optic nerve head (ONH) features from color fundus images, to determine the relative importance of these features in referr...