Major depressive disorder (MDD) is associated with substantial morbidity and mortality, yet its diagnosis and treatment rates remain low due to its diverse and often overlapping clinical manifestations. In this context, electroencephalography (EEG) h...
INTRODUCTION: Bipolar disorder (BD) and major depressive disorder (MDD) have overlapping clinical presentations which may make it difficult for clinicians to distinguish them potentially resulting in misdiagnosis. This study combined structural MRI a...
Major Depressive Disorder (MDD) is a prevalent mental health condition that often begins in adolescence, with significant long-term implications. Indicated prevention programs targeting adolescents with mild symptoms have shown efficacy, yet the meth...
BMC medical informatics and decision making
39962516
BACKGROUND: Depressive disorder, particularly major depressive disorder (MDD), significantly impact individuals and society. Traditional analysis methods often suffer from subjectivity and may not capture complex, non-linear relationships between ris...
BACKGROUND: Early diagnosis of depression is crucial, and speech-based early diagnosis of depression is promising, but insufficient data and lack of theoretical support make it difficult to be applied. Therefore, it is valuable to combine psychiatric...
BACKGROUND: Lack of widespread use of the Patient Health Questionnaire 9-item (PHQ-9) in clinical practice inhibits measurement of treatment follow-up for patients with major depressive disorder (MDD). This study developed, validated and applied a ma...
Journal of computational biology : a journal of computational molecular cell biology
39899351
The extraction of biomarkers from functional connectivity (FC) in the brain is of great significance for the diagnosis of mental disorders. In recent years, with the development of deep learning, several methods have been proposed to assist in the di...
Major depressive disorder (MDD) is a psychiatric disorder characterized by persistent lethargy that can lead to suicide in severe cases. Hence, timely and accurate diagnosis and treatment are crucial. Previous neuroscience studies have demonstrated t...
BACKGROUND: Evidence indicates that patients with Major Depressive Disorder (MDD) exhibit a senescence phenotype or an increased susceptibility to premature senescence. However, the relationship between senescence-related genes (SRGs) and MDD remains...
BACKGROUND: Major depressive disorder (MDD) is among the leading causes of disability worldwide and treatment efficacy is variable across patients. Polymorphisms in cytochrome P450 2C19 (CYP2C19) play a role in response and side effects to medication...