Laboratory investigation; a journal of technical methods and pathology
Feb 11, 2021
Most biomedical datasets, including those of 'omics, population studies, and surveys, are rectangular in shape and have few missing data. Recently, their sample sizes have grown significantly. Rigorous analyses on these large datasets demand consider...
OBJECTIVE: We developed and investigated the feasibility of a machine learning-based automated rating for the 2 cardinal symptoms of Parkinson disease (PD): resting tremor and bradykinesia.
PURPOSE: To compare the performance of a novel convolutional neural network (CNN) classifier and human graders in detecting angle closure in EyeCam (Clarity Medical Systems, Pleasanton, California, USA) goniophotographs.
Background Studies on the optimal CT section thickness for detecting subsolid nodules (SSNs) with computer-aided detection (CAD) are lacking. Purpose To assess the effect of CT section thickness on CAD performance in the detection of SSNs and to inve...
Early differential diagnosis of several motor neuron diseases (MNDs) is extremely challenging due to the high number of overlapped symptoms. The routine clinical practice is based on clinical history and examination, usually accompanied by electrophy...
. At present, the research methods for image genetics of Alzheimer's disease based on machine learning are mainly divided into three steps: the first step is to preprocess the original image and gene information into digital signals that are easy to ...
Computational and mathematical methods in medicine
Feb 8, 2021
At present, human health is threatened by many diseases, and lung cancer is one of the most dangerous tumors that threaten human life. In most developing countries, due to the large population and lack of medical resources, it is difficult for doctor...
PURPOSE: Stage is an important feature to identify in retinal images of infants at risk of retinopathy of prematurity (ROP). The purpose of this study was to implement a convolutional neural network (CNN) for binary detection of stages 1, 2, and 3 in...
BACKGROUND: Benign breast disease (BBD) is a strong breast cancer risk factor, but identifying patients that might develop invasive breast cancer remains a challenge.
A common problem found in real-word medical image classification is the inherent imbalance of the positive and negative patterns in the dataset where positive patterns are usually rare. Moreover, in the classification of multiple classes with neural ...