AIMC Topic: Disease Progression

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Higher effect sizes for the detection of accelerated brain volume loss and disability progression in multiple sclerosis using deep-learning.

Computers in biology and medicine
PURPOSE: Clinical validation of "BrainLossNet", a deep learning-based method for fast and robust estimation of brain volume loss (BVL) from longitudinal T1-weighted MRI, for the detection of accelerated BVL in multiple sclerosis (MS) and for the disc...

Identification of key biomarkers for predicting atherosclerosis progression in polycystic ovary syndrome via bioinformatics analysis and machine learning.

Computers in biology and medicine
OBJECTIVE: Polycystic ovary syndrome (PCOS) is one of the most significant cardiovascular risk factors, playing vital roles in various cardiovascular diseases such as atherosclerosis (AS). This study attempted to explore key biomarkers for predicting...

Development of the machine learning model that is highly validated and easily applicable to predict radiographic knee osteoarthritis progression.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Many models using the aid of artificial intelligence have been recently proposed to predict the progression of knee osteoarthritis. However, previous models have not been properly validated with an external data set or have reported poor predictive p...

Nuclear magnetic resonance-based metabolomics with machine learning for predicting progression from prediabetes to diabetes.

eLife
BACKGROUND: Identification of individuals with prediabetes who are at high risk of developing diabetes allows for precise interventions. We aimed to determine the role of nuclear magnetic resonance (NMR)-based metabolomic signature in predicting the ...

Radiomics-Based Support Vector Machine Distinguishes Molecular Events Driving the Progression of Lung Adenocarcinoma.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
INTRODUCTION: An increasing number of early-stage lung adenocarcinomas (LUAD) are detected as lung nodules. The radiological features related to LUAD progression warrant further investigation. Exploration is required to bridge the gap between radiomi...

Predicting multiple sclerosis disease progression and outcomes with machine learning and MRI-based biomarkers: a review.

Journal of neurology
Multiple sclerosis (MS) is a demyelinating neurological disorder with a highly heterogeneous clinical presentation and course of progression. Disease-modifying therapies are the only available treatment, as there is no known cure for the disease. Car...

Machine learning-based model for worsening heart failure risk in Chinese chronic heart failure patients.

ESC heart failure
AIMS: This study aims to develop and validate an optimal model for predicting worsening heart failure (WHF). Multiple machine learning (ML) algorithms were compared, and the results were interpreted using SHapley Additive exPlanations (SHAP). A clini...