BACKGROUND: Precision medicine requires a stratification of patients by disease presentation that is sufficiently informative to allow for selecting treatments on a per-patient basis. For many diseases, such as neurological disorders, this stratifica...
Metabolic syndrome and related disorders
Nov 1, 2019
We investigated the prevalence and the most relevant features of nonalcoholic steatohepatitis (NASH), a stage of nonalcoholic fatty liver disease, (NAFLD) in which the inflammation of hepatocytes can lead to increased cardiovascular risk, liver fibr...
Neuroanatomical pattern classification using support vector machines (SVMs) has shown promising results in classifying Multiple Sclerosis (MS) patients based on individual structural magnetic resonance images (MRI). To determine whether pattern class...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
Early prediction of diseased brain conditions is critical for curing illness and preventing irreversible neuronal dysfunction and loss. Generically regarding the different neuroimaging modalities as filtered, complementary insights of brain's anatomi...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
Parkinson's Disease (PD) is the second most prevalent progressive neurological disorder around the world with high incidence rates for seniors. Since most symptoms are exposed in the later stages of the disease, early diagnosis of PD is essential for...
Amyotrophic lateral sclerosis (ALS) is a complex progressive neurodegenerative disorder with an estimated prevalence of about 5 per 100,000 people in the United States. In this study, the ALS disease progression is measured by the change of Amyotroph...
Clinical and translational gastroenterology
May 22, 2019
OBJECTIVES: Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic adenocarcinoma. Artificial intelligence (AI) is a mathematical concept whose implementation automates learning and recognizing data patterns. The aim of ...
Journal of the American Medical Informatics Association : JAMIA
May 1, 2019
OBJECTIVE: Participants enrolled into randomized controlled trials (RCTs) often do not reflect real-world populations. Previous research in how best to transport RCT results to target populations has focused on weighting RCT data to look like the tar...
Investigative ophthalmology & visual science
Feb 1, 2019
PURPOSE: To develop and assess a method for predicting the likelihood of converting from early/intermediate to advanced wet age-related macular degeneration (AMD) using optical coherence tomography (OCT) imaging and methods of deep learning.