AI Medical Compendium Topic:
Disease Progression

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Deep learning for clustering of multivariate clinical patient trajectories with missing values.

GigaScience
BACKGROUND: Precision medicine requires a stratification of patients by disease presentation that is sufficiently informative to allow for selecting treatments on a per-patient basis. For many diseases, such as neurological disorders, this stratifica...

Relevant Features in Nonalcoholic Steatohepatitis Determined Using Machine Learning for Feature Selection.

Metabolic syndrome and related disorders
We investigated the prevalence and the most relevant features of nonalcoholic steatohepatitis (NASH), a stage of nonalcoholic fatty liver disease, (NAFLD) in which the inflammation of hepatocytes can lead to increased cardiovascular risk, liver fibr...

MRI-based prediction of conversion from clinically isolated syndrome to clinically definite multiple sclerosis using SVM and lesion geometry.

Brain imaging and behavior
Neuroanatomical pattern classification using support vector machines (SVMs) has shown promising results in classifying Multiple Sclerosis (MS) patients based on individual structural magnetic resonance images (MRI). To determine whether pattern class...

[French ccAFU guidelines – Update 2018–2020: Bladder cancer].

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie
OBJECTIVE: To propose updated French guidelines for non-muscle invasive (NMIBC) and muscle-invasive (MIBC) bladder cancers.

Multimodal Data Fusion of Deep Learning and Dynamic Functional Connectivity Features to Predict Alzheimer's Disease Progression.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Early prediction of diseased brain conditions is critical for curing illness and preventing irreversible neuronal dysfunction and loss. Generically regarding the different neuroimaging modalities as filtered, complementary insights of brain's anatomi...

Automatic Classification and Monitoring of Denovo Parkinson's Disease by Learning Demographic and Clinical Features.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Parkinson's Disease (PD) is the second most prevalent progressive neurological disorder around the world with high incidence rates for seniors. Since most symptoms are exposed in the later stages of the disease, early diagnosis of PD is essential for...

Model-Based and Model-Free Techniques for Amyotrophic Lateral Sclerosis Diagnostic Prediction and Patient Clustering.

Neuroinformatics
Amyotrophic lateral sclerosis (ALS) is a complex progressive neurodegenerative disorder with an estimated prevalence of about 5 per 100,000 people in the United States. In this study, the ALS disease progression is measured by the change of Amyotroph...

Usefulness of Deep Learning Analysis for the Diagnosis of Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Clinical and translational gastroenterology
OBJECTIVES: Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic adenocarcinoma. Artificial intelligence (AI) is a mathematical concept whose implementation automates learning and recognizing data patterns. The aim of ...

An outcome model approach to transporting a randomized controlled trial results to a target population.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Participants enrolled into randomized controlled trials (RCTs) often do not reflect real-world populations. Previous research in how best to transport RCT results to target populations has focused on weighting RCT data to look like the tar...

Deep Learning for Prediction of AMD Progression: A Pilot Study.

Investigative ophthalmology & visual science
PURPOSE: To develop and assess a method for predicting the likelihood of converting from early/intermediate to advanced wet age-related macular degeneration (AMD) using optical coherence tomography (OCT) imaging and methods of deep learning.