Unplanned admissions for worsening heart failure (WHF) are the largest resource cost in heart failure (HF) management. Despite advances in pharmacological agents and interventional therapy, HF remains a global epidemic. One crucial-and costly-gap in ...
Studies in health technology and informatics
Aug 7, 2025
Chronic Kidney Disease (CKD) is a prevalent and progressive condition that can lead to end-stage renal disease (ESRD) if left unmanaged. Accurate prediction of CKD progression, particularly in patients with CKD stages 3-5, is essential for early inte...
Studies in health technology and informatics
Aug 7, 2025
The rapid symptom change of Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) makes it critical to have time-sensitive prediction models. However, most current machine learning models studying AECOPD use clinical and laboratory dat...
BACKGROUND: Glucagon-like Peptide-1 Receptor Agonists (GLP1RA) may reduce asthma exacerbation (AE) risk, but it is unclear which populations benefit most. Recent pharmacoepidemiologic studies have employed iterative causal forest (iCF), a machine lea...
BACKGROUND: We previously proposed a neurocognitive model of psychosis in which reduced morphometric hippocampal-cortical connectivity precedes impaired episodic memory, social cognition, negative symptoms, and functional outcome. We provided support...
BACKGROUND: Visual scoring of tubular damage has limitations in capturing the full spectrum of structural changes and prognostic potential. Here, we investigated if computationally quantified tubular features can enhance prognostication and reveal sp...
PURPOSE OF REVIEW: This review explores the use of brain age estimation from MRI scans as a biomarker of brain health. With disorders like Alzheimer's and Parkinson's increasing globally, there is an urgent need for early detection tools that can ide...
Chronic kidney disease (CKD) poses a significant risk for diabetes patients, often leading to severe complications. Early and accurate CKD stage detection is crucial for timely intervention. However, it remains challenging due to its asymptomatic pro...
Amyotrophic lateral sclerosis & frontotemporal degeneration
Aug 1, 2025
Traditionally understood as a motor neuron disease, amyotrophic lateral sclerosis (ALS) is now recognized to involve broader neurodegenerative processes, including the oculomotor system. This narrative review summarizes current evidence on oculomotor...
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