AIMC Topic: Drosophila

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Predicting individual neuron responses with anatomically constrained task optimization.

Current biology : CB
Artificial neural networks trained to solve sensory tasks can develop statistical representations that match those in biological circuits. However, it remains unclear whether they can reproduce properties of individual neurons. Here, we investigated ...

FlyIT: Drosophila Embryogenesis Image Annotation based on Image Tiling and Convolutional Neural Networks.

IEEE/ACM transactions on computational biology and bioinformatics
With the rise of image-based transcriptomics, spatial gene expression data has become increasingly important for understanding gene regulations from the tissue level down to the cell level. Especially, the gene expression images of Drosophila embryos...

Quantifying influence of human choice on the automated detection of Drosophila behavior by a supervised machine learning algorithm.

PloS one
Automated quantification of behavior is increasingly prevalent in neuroscience research. Human judgments can influence machine-learning-based behavior classification at multiple steps in the process, for both supervised and unsupervised approaches. S...

Intelligent image-based deformation-assisted cell sorting with molecular specificity.

Nature methods
Although label-free cell sorting is desirable for providing pristine cells for further analysis or use, current approaches lack molecular specificity and speed. Here, we combine real-time fluorescence and deformability cytometry with sorting based on...

Decentralized control of insect walking: A simple neural network explains a wide range of behavioral and neurophysiological results.

PLoS computational biology
Controlling the six legs of an insect walking in an unpredictable environment is a challenging task, as many degrees of freedom have to be coordinated. Solutions proposed to deal with this task are usually based on the highly influential concept that...

Fully Automated Leg Tracking in Freely Moving Insects using Feature Learning Leg Segmentation and Tracking (FLLIT).

Journal of visualized experiments : JoVE
The Drosophila model has been invaluable for the study of neurological function and for understanding the molecular and cellular mechanisms that underlie neurodegeneration. While fly techniques for the manipulation and study of neuronal subsets have ...

Deep learning for automated detection of Drosophila suzukii: potential for UAV-based monitoring.

Pest management science
BACKGROUND: The fruit fly Drosophila suzukii, or spotted wing drosophila (SWD), is a serious pest worldwide, attacking many soft-skinned fruits. An efficient monitoring system that identifies and counts SWD in crops and their surroundings is therefor...

Predicting gene regulatory interactions based on spatial gene expression data and deep learning.

PLoS computational biology
Reverse engineering of gene regulatory networks (GRNs) is a central task in systems biology. Most of the existing methods for GRN inference rely on gene co-expression analysis or TF-target binding information, where the determination of co-expression...

DeTerm: Software for automatic detection of neuronal dendritic branch terminals via an artificial neural network.

Genes to cells : devoted to molecular & cellular mechanisms
Dendrites of neurons receive and process synaptic or sensory inputs. The Drosophila class IV dendritic arborization (da) neuron is an established model system to explore molecular mechanisms of dendrite morphogenesis. The total number of dendritic br...

A neural data structure for novelty detection.

Proceedings of the National Academy of Sciences of the United States of America
Novelty detection is a fundamental biological problem that organisms must solve to determine whether a given stimulus departs from those previously experienced. In computer science, this problem is solved efficiently using a data structure called a B...