AIMC Topic: Drug Delivery Systems

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A new era of psoriasis treatment: Drug repurposing through the lens of nanotechnology and machine learning.

International journal of pharmaceutics
Psoriasis is a persistent inflammatory skin disorder characterized by hyper-proliferation and abnormal epidermal differentiation. Conventional treatments such as; topical therapies, phototherapy, systemic immune modulators, and biologics aim to relie...

Using mathematical modelling and AI to improve delivery and efficacy of therapies in cancer.

Nature reviews. Cancer
Mathematical modelling has proven to be a valuable tool in predicting the delivery and efficacy of molecular, antibody-based, nano and cellular therapy in solid tumours. Mathematical models based on our understanding of the biological processes at su...

Utilizing machine learning for predicting drug release from polymeric drug delivery systems.

Computers in biology and medicine
Polymeric drug delivery systems (PDDS) play a crucial role in controlled drug release, providing improved therapeutic outcomes. However, formulating PDDS and predicting their release profiles remain challenging due to their complex structures and the...

Cooperative Magnetic Interfacial Microrobot Couple for Versatile Non-Contact Biomedical Applications.

Advanced materials (Deerfield Beach, Fla.)
Magnetic interfacial microrobots are increasingly recognized as a promising approach for potential biomedical applications ranging from electronic functionalization to minimally invasive surgery and targeted drug delivery. Nevertheless, existing rese...

Translational nanorobotics breaking through biological membranes.

Chemical Society reviews
In the dynamic realm of translational nanorobotics, the endeavor to develop nanorobots carrying therapeutics in rational applications necessitates a profound understanding of the biological landscape of the human body and its complexity. Within this...

Revolutionizing prostate cancer therapy: Artificial intelligence - Based nanocarriers for precision diagnosis and treatment.

Critical reviews in oncology/hematology
Prostate cancer is one of the major health challenges in the world and needs novel therapeutic approaches to overcome the limitations of conventional treatment. This review delineates the transformative potential of artificial intelligence (AL) in en...

Harnessing machine learning algorithms for the prediction and optimization of various properties of polylactic acid in biomedical use: a comprehensive review.

Biomedical materials (Bristol, England)
Machine learning (ML) has emerged as a transformative tool in various industries, driving advancements in key tasks like classification, regression, and clustering. In the field of chemical engineering, particularly in the creation of biomedical devi...

Advancements and Prospects in Nanorobotic Applications for Ophthalmic Therapy.

ACS biomaterials science & engineering
This study provides a bibliometric and bibliographic review of emerging applications of micro- and nanotechnology in treating ocular diseases, with a primary focus on glaucoma. We aim to identify key research trends and analyze advancements in device...

AlgaeSperm: Microalgae-Based Soft Magnetic Microrobots for Targeted Tumor Treatment.

Small (Weinheim an der Bergstrasse, Germany)
Magnetic microrobots are significant platforms for targeted drug delivery, among which sperm-inspired types have attracted much attention due to their flexible undulation. However, mass production of sperm-like soft magnetic microrobots with high-spe...

Robotic Microcapsule Assemblies with Adaptive Mobility for Targeted Treatment of Rugged Biological Microenvironments.

ACS nano
Microrobots are poised to transform biomedicine by enabling precise, noninvasive procedures. However, current magnetic microrobots, composed of solid monolithic particles, present fundamental challenges in engineering intersubunit interactions, limit...