AIMC Topic: Drug Delivery Systems
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3D printed dosage forms, where are we headed?
Expert opinion on drug delivery
Jul 24, 2024
INTRODUCTION: 3D Printing (3DP) is an innovative fabrication technology that has gained enormous popularity through its paradigm shifts in manufacturing in several disciplines, including healthcare. In this past decade, we have witnessed the impact o...
Neurological insights into brain-targeted cancer therapy and bioinspired microrobots.
Drug discovery today
Jul 17, 2024
Cancer, a multifaceted and pernicious disease, continuously challenges medicine, requiring innovative treatments. Brain cancers pose unique and daunting challenges due to the intricacies of the central nervous system and the blood-brain barrier. In t...
Machine learning in drug delivery.
Journal of controlled release : official journal of the Controlled Release Society
Jun 26, 2024
For decades, drug delivery scientists have been performing trial-and-error experimentation to manually sample parameter spaces and optimize release profiles through rational design. To enable this approach, scientists spend much of their career learn...
Harnessing Disparities in Magnetic Microswarms: From Construction to Collaborative Tasks.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 13, 2024
Individual differences in size, experience, and task specialization in natural swarms often result in heterogeneity and hierarchy, facilitating efficient and coordinated task accomplishment. Drawing inspiration from this phenomenon, a general strateg...
Nose-to-Brain Drug Delivery and Physico-Chemical Properties of Nanosystems: Analysis and Correlation Studies of Data from Scientific Literature.
International journal of nanomedicine
Jun 11, 2024
BACKGROUND: In the last few decades, nose-to-brain delivery has been investigated as an alternative route to deliver molecules to the Central Nervous System (CNS), bypassing the Blood-Brain Barrier. The use of nanotechnological carriers to promote dr...
Advances in artificial intelligence for drug delivery and development: A comprehensive review.
Computers in biology and medicine
Jun 7, 2024
Artificial intelligence (AI) has emerged as a powerful tool to revolutionize the healthcare sector, including drug delivery and development. This review explores the current and future applications of AI in the pharmaceutical industry, focusing on dr...
Fillable Magnetic Microrobots for Drug Delivery to Cardiac Tissues In Vitro.
Advanced healthcare materials
May 29, 2024
Many cardiac diseases, such as arrhythmia or cardiogenic shock, cause irregular beating patterns that must be regulated to prevent disease progression toward heart failure. Treatments can include invasive surgery or high systemic drug dosages, which ...
POxload: Machine Learning Estimates Drug Loadings of Polymeric Micelles.
Molecular pharmaceutics
May 28, 2024
Block copolymers, composed of poly(2-oxazoline)s and poly(2-oxazine)s, can serve as drug delivery systems; they form micelles that carry poorly water-soluble drugs. Many recent studies have investigated the effects of structural changes of the polyme...
Engineering mannose-functionalized nanostructured lipid carriers by sequential design using hybrid artificial intelligence tools.
Drug delivery and translational research
May 9, 2024
Nanostructured lipid carriers (NLCs) hold significant promise as drug delivery systems (DDS) owing to their small size and efficient drug-loading capabilities. Surface functionalization of NLCs can facilitate interaction with specific cell receptors,...
Development and comparison of machine learning models for in-vitro drug permeation prediction from microneedle patch.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
May 6, 2024
The field of machine learning (ML) is advancing to a larger extent and finding its applications across numerous fields. ML has the potential to optimize the development process of microneedle patch by predicting the drug release pattern prior to its ...
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