OBJECTIVE: To create an automated PET/CT segmentation method and radiomics model to forecast Mismatch repair (MMR) and TP53 gene expression in endometrial cancer patients, and to examine the effect of gene expression variability on image texture feat...
European journal of obstetrics, gynecology, and reproductive biology
Jun 4, 2025
OBJECTIVE: Hysteroscopy is commonly used for diagnosing benign endometrial conditions, but its diagnostic performance in malignancies post-treatment surveillance has not been evaluated. This study evaluated the correlation between hysteroscopic appea...
PURPOSE: Endometrial cancer (EC) is the most common gynecologic cancer in the United States with rising incidence and mortality. Despite optimal treatment, 15%-20% of all patients will recur. To better select patients for adjuvant therapy, it is impo...
PURPOSE: To evaluate the efficacy of deep learning reconstruction (DLR) in diffusion-weighted imaging (DWI) with single-shot echo-planar imaging (SSEPI) for endometrial cancer, compared to multiplexed sensitivity-encoding (MUSE) DWI.
BACKGROUND: Endometrial cancer is one of the most common gynecological tumors, and early screening and diagnosis are crucial for its treatment. Research on the application of artificial intelligence (AI) in the diagnosis of endometrial cancer is incr...
The exploration of deep learning techniques for predicting various biological characteristics of endometrial cancer (EC) is of significant importance. The objective of this study was to develop an optimized radiomics scheme combining multiparametric ...
PURPOSE: Microsatellite instability (MSI), caused by defects in mismatch repair (MMR) genes, serves as a critical molecular biomarker with therapeutic implications for endometrial cancer (EC). This study aims to assess the diagnostic performance of r...
BACKGROUND: Endometrial cancer is one of the most common tumors of the female reproductive system and ranks third in the world list of gynecological malignancies that cause death. However, due to the privacy and complexity of pathology images, it is ...
The key roles of Major Histocompatibility Complex (MHC) Class I and II molecules in the immune system are well established. This study aims to develop a novel machine learning framework for predicting antigen peptide presentation by MHC Class I and I...
Cancer immunology, immunotherapy : CII
Feb 1, 2025
With the incorporation of immune checkpoint inhibitors into the treatment of endometrial cancer (EC), a deeper understanding of the tumor immune microenvironment is critical. Tertiary lymphoid structures (TLSs) are considered favorable prognostic fac...
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